The VKORC1 gene homepage

General information
Gene symbol VKORC1
Gene name vitamin K epoxide reductase complex, subunit 1
Chromosome 16
Chromosomal band p11.2
Imprinted Unknown
Genomic reference NG_011564.1
Transcript reference NM_024006.4
Exon/intron information NM_024006.4 exon/intron table
Associated with diseases DMBCYP2A6, VKCFD2
Citation reference(s) -
Refseq URL Genomic reference sequence
Curators (1) Global Variome, with Curator vacancy
Total number of public variants reported 193
Unique public DNA variants reported 25
Individuals with public variants 175
Hidden variants 2
Notes VKORC1 reference haplotypes in this database. Download the current VKORC1 reference haplotype list (ver.2014-10-20).
Date created May 03, 2013
Date last updated April 19, 2024
Version VKORC1:240419

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
Reading frame checker The Reading-frame checker generates a prediction of the effect of whole-exon changes. Active for: NM_024006.4.
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
Homepage URL http://www.LOVD.nl/VKORC1
External URL PharmGKB
HGNC 23663
Entrez Gene 79001
PubMed articles VKORC1
OMIM - Gene 608547
OMIM - Diseases DMBCYP2A6 (metabolism, drug, resistance, coumarin)
VKCFD2 (vitamin K-dependent clotting factors, combined deficiency of, type 2 (VKCFD-2))
HGMD VKORC1
GeneCards VKORC1
GeneTests VKORC1
Orphanet VKORC1


Active transcripts


ID     

Chr     

Name     

NCBI ID     

NCBI Protein ID     

DescendingVariants     
00022610 16 transcript variant 1 NM_024006.4 NP_076869.1 193


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