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LOVD v.2.0 - Leiden Open Variation Database
Online gene-centered collection and display of DNA variations
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For all details about LOVD, see our LOVD flyer! (last updated February 24th, 2010) |
| LOVD 2.0 build 24 released |
2010-02-01 |
Today, LOVD 2.0-24 has been released. New features implemented, amongst others: Updated LOVD's API greatly by implementing genomic-location based searching for genes and variants in a non-exact matching type, added column hiding on more variant overviews, enabled GenBank uploader script to extract important transcript IDs. Bugs fixed, amongst others: Fixed some issues with viewing LOVD data in the UCSC genome browser, fixed some issues of malfunctioning functionalities when using SSL, fixed problem where LOVD was sometimes shown as a page full of HTML code, fixed a problem with Find & Replace.
See the changelog.
Download the new build.
LOVD modules included: Mutalyzer 0.7, reCAPTCHA 0.1, ShowMaxDBID 0.4
LOVD scripts included: ParseRefSeq 2.11, Reading Frame Checker 1.0, UploadGenBank 1.4
Manual version included: December 11th, 2009. |
| LOVD 2.0 build 23 released |
2009-12-07 |
Today, LOVD 2.0-23 has been released. New features implemented, amongst others: Improved the LOVD webservice API greatly; gene information can be queried and it allows searches for genomic DNA positions as well as coding DNA positions. Variants in correctly configured genes will be mapped to the genome, and links to the UCSC genome browser and the NCBI sequence viewer have been made available. Also the feature to temporary hide columns from the view has been enhanced, the variant overviews now show an info box to explain the current view, and the Reading Frame Checker script now generates HGVS notation. Bugs fixed, amongst others: Fixed some issues with the Reference Sequence Parser and the variant statistics summary overview.
Please NOTE that upgrading to 2.0-23 may take a long time if your database contains a lot of genes and variants!
See the changelog.
Download the new build.
LOVD modules included: Mutalyzer 0.7, reCAPTCHA 0.1, ShowMaxDBID 0.4
LOVD scripts included: ParseRefSeq 2.10, Reading Frame Checker 1.0, UploadGenBank 1.3
Manual version included: December 1st, 2009. |
| Announcing LOVD 3.0 |
2009-10-29 |
We would like to announce that the development has started of a new LOVD branch, LOVD 3.0. In the last year, we have refined the data model, which allows for more flexibility in data storage and data sharing. The look and feel of the system will not change too much; however the way data can be viewed will change according to the new data model.
Because the focus in development will move somewhat, releases of LOVD 2.0 will not be as frequent as normal. The next LOVD build, 2.0-23, will be released December 7nd, 2009. So no November release! |
| LOVD 2.0 build 22 released |
2009-10-05 |
Today, LOVD 2.0-22 has been released. New features implemented, amongst others: Improved user and submitter overview by adding icons to indicate their status, created LOVD RESTful webservice (currently undocumented), added Reading Frame Checker script (works in conjunction with the Reference Sequence Parser). Bugs fixed, amongst others: Fixed some problems with reloading the Mutalyzer module when using a different GenBank file, working in different LOVD windows in different genes sometimes caused LOVD to edit the wrong gene, Internet Explorer did not submit the search fields above the variant listings, fixed some problems in the Reference Sequence Parser.
See the changelog.
Download the new build.
LOVD modules included: Mutalyzer 0.6, reCAPTCHA 0.1, ShowMaxDBID 0.4
LOVD scripts included: ParseRefSeq 2.9, Reading Frame Checker 1.0, UploadGenBank 1.3
Manual version included: September 18th, 2009. |
| LOVD Windows local install CD 2.0-21 released |
2009-09-21 |
Today, the LOVD Windows local install CD 2.0-21 has been released. Compared to the previous release, some programs and files from the xampp software which were not used, to keep the size of the CD down.
This CD includes:
- XAMPP 1.6.6a
- Apache HTTPD 2.2.8
- MySQL 5.0.51a
- PHP 5.2.5
- phpMyAdmin 2.11.4
- Mercury Mail Transport System 4.52
- LOVD 2.0-21
See the changelog.
Download the new CD! |
News older than 6 months can be found in the archive.
| Last modified 2010/02/01 17:03:30 CET |
When using or discussing LOVD please refer to:
Fokkema IFAC, Den Dunnen JT and Taschner PEM (2005). LOVD: easy creation of a locus-specific sequence variation database using an "LSDB-in-a-Box" approach.
Hum Mutat. 2005 Aug;26(2):63-8.
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