Information For all details about LOVD, see our LOVD flyer! (last updated June 6th, 2013)

Leiden Open Variation Database 3.0

Question If you are looking for a specific gene database, please check the list of gene variant databases in our list of LSDBs, or in the list of registered LOVD installations. Our LSDB list can also be reached by typing GENESYMBOL.lovd.nl in your browser address bar, like DMD.lovd.nl.

LOVD
LOVD stands for Leiden Open (source) Variation Database.
LOVD's purpose : To provide a flexible, freely available tool for Gene-centered collection and display of DNA variations. LOVD 3.0 extends this idea to also provide patient-centered data storage and storage of NGS data, even of variants outside of genes. LOVD is open source, released under the GPL license, and is actively being improved, currently we have releases every month.

To maintain a high quality of the data stored, LOVD connects with various resources, like HGNC, NCBI, EBI and Mutalyzer.

LOVD 3.0 is the successor of LOVD 2.0. Do you want to know more about the changes between LOVD 2.0 and 3.0?
Want to see what LOVD 3.0 looks like?

Mutalyzer
LOVD features integration with the Mutalyzer sequence variant nomenclature checker, allowing for direct nomenclature checking of sequence variants during the submission process.

Last modified 2014/08/25 14:47:29 CEST

When using or discussing LOVD please refer to:
Fokkema IF, Taschner PE, Schaafsma GC, Celli J, Laros JF, den Dunnen JT (2011). LOVD v.2.0: the next generation in gene variant databases. Hum Mutat. 2011 May;32(5):557-63.

A recommended system of the Human Variome Project LOVD has received funding from the European Community's Seventh Framework Programme
(FP7/2007-2013) under grant agreement nº 200754 - the GEN2PHEN project.
©2004-2014 Leiden University Medical Center, Netherlands
Ivo F.A.C. Fokkema BSc., Prof. Johan T. den Dunnen PhD