List of public LOVD installations

Question If you are looking for a specific gene database, please also check our list of LSDBs.

Please note that the latest available build is always installed on our Leiden server. We offer free use of this LOVD installation for those interested, e.g. to maintain/start a LSDB. Contact us for more information.

Show only LOVDs with gene symbol:

You can also download this list to see the complete list of genes in the databases.

In total: 1,026,283,196 variants (6,624,453 unique) in 1,273,990 individuals in 69 LOVD installations.
http://bipmed.iqm.unicamp.br/snparray_296/ LOVD 3.0-21 16643 genes 267838856 variants
BIPMed SNP Array - HG38 A1BG-AS1,A1CF,A2M,A2M-AS1,A2ML1,A2MP1,A3GALT2,A4GALT,A4GN... 895813 unique
http://bipmed.iqm.unicamp.br/snparray_hg19/ LOVD 3.0-21 15440 genes 267807776 variants
BIPMed SNP Array - HG19 A1CF,A2M,A2M-AS1,A2ML1,A2MP1,A3GALT2,A4GALT,A4GNT,AACS,AA... 893557 unique
http://bipmed.iqm.unicamp.br/snparray/ LOVD 3.0-20 17391 genes 222715116 variants
BIPMed SNP Array A1BG-AS1,A1CF,A2M,A2M-AS1,A2ML1,A2MP1,A3GALT2,A4GALT,A4GN... 902273 unique
http://bipmed.iqm.unicamp.br/wes_hg19/ LOVD 3.0-21 18203 genes 197345407 variants
BIPMed WES - HG19 A1BG,A1CF,A2M,A2M-AS1,A2ML1,A3GALT2,A4GALT,A4GNT,AAAS,AAC... 824599 unique
http://bipmed.iqm.unicamp.br/ LOVD 3.0-20 20930 genes 66158522 variants
BIPMed WES A1BG,A1BG-AS1,A1CF,A2M,A2M-AS1,A2ML1,A2MP1,A3GALT2,A4GALT... 622610 unique
http://databases.lovd.nl/whole_genome/ LOVD 3.0-20a 22002 genes 1998175 variants
Whole genome datasets A1BG,A1BG-AS1,A1CF,A2M,A2M-AS1,A2ML1,A2MP1,A4GALT,A4GNT,A... 1998135 unique
https://databases.lovd.nl/shared/ LOVD 3.0-21d 22990 genes 1689295 variants
Global Variome shared LOVD A1BG,A1BG-AS1,A1CF,A2LD1,A2M,A2M-AS1,A2ML1,A2MP1,A3GALT2,... 256992 unique
http://proteomics.bio21.unimelb.edu.au/lovd/ LOVD 3.0-07 14772 genes 239690 variants
LOVD - Leiden Open Variation Database A1BG,A1BG-AS1,A1CF,A2M,A2ML1,A4GALT,A4GNT,AAAS,AACS,AACSP... 152241 unique
http://bipmed.iqm.unicamp.br/cfa/ LOVD 3.0-20 41 genes 134333 variants
Craniofacial anomalies APOC2,APOC4-APOC2,AXIN2,BCL3,BMP4,CLPTM1,DVL2,ERBB2,FGF22... 257 unique
https://ab-openlab.csir.res.in/mitolsdb/ LOVD 2.0-35 37 genes 112662 variants
MitoLSDB MTATP6,MTATP8,MTCO1,MTCO2,MTCO3,MTCYB,MTND1,MTND2,MTND3,M... 4660 unique
http://www.genomed.zju.edu.cn/LOVD3/ LOVD 3.0-21 113 genes 111082 variants
Zhejiang University Center for Genetic and Genomic Medicine (ZJU-CGGM) & DIAN DIAGNOSTICS ABCC9,ACTC1,ACTN2,AKAP9,ANK2,APC,AXIN2,BARD1,BCL11A,BRCA1... 394 unique
http://HCI-LOVD.hci.utah.edu LOVD 2.0-33 8 genes 26167 variants
LOVD - human mismatch repair genes MLH1,MLH1_priors,MSH2,MSH2_priors,MSH6,MSH6_priors,PMS2,P... 26167 unique
https://grenada.lumc.nl/LOVD2/Usher_montpellier/ LOVD 2.0-37 20 genes 23521 variants
Retinal and hearing impairment genetic mutation database CDH23,CEACAM16,CERKL,CHM,CLDN14,CLRN1,GPR98,MYO15A,MYO6,M... 3656 unique
http://chromium.lovd.nl/LOVD2/TSC/ LOVD 2.0-37 2 genes 20480 variants
Tuberous sclerosis database TSC1,TSC2 3970 unique
https://mseqdr.org/MITO/ LOVD 3.0-21 1628 genes 17310 variants
MSeqDR-LSDB Mitochondrial Disease Locus Specific Database AADAT,AARS2,AASS,ABAT,ABCA13,ABCA9,ABCB10,ABCB6,ABCB7,ABC... 15004 unique
http://bioinf.suda.edu.cn/NDDvarbase/LOVDv.3.0/ LOVD 3.0-20a 289 genes 6374 variants
NDDVD - Neurodegenerative Diseases Variation Database ABCA7,ABCB1,ADCY5,ADORA1,ADRA1A,AFG3L2,AGBL3,ALS2,ANG,ANK... 4959 unique
http://www.inc.gob.ar/sither/ LOVD 3.0-19 44 genes 6018 variants
AKT1,APC,ATM,BAP1,BARD1,BLM,BMPR1A,BRCA1,BRCA2,BRIP1,CDH1... 661 unique
https://oi.gene.le.ac.uk/ LOVD 2.0-36 20 genes 4826 variants
Osteogenesis Imperfecta Variant Database BMP1,COL1A1,COL1A2,CREB3L1,CRTAP,FAM46A,FKBP10,IFITM5,P3H... 2257 unique
http://databases.lovd.nl/DNA_profiles/ LOVD 3.0-20a 0 genes 3414 variants
LOVD - Leiden Open Variation Database 667 unique
http://rb1-lovd.d-lohmann.de/ LOVD 2.0-34 1 gene 3396 variants
rb1-lsdb RB1 1753 unique
http://lovd.bx.psu.edu/ LOVD 2.0-36 37 genes 2311 variants
The Globin Gene Server ALOX5AP,AQP9,ARG2,ASS1,ATRX,BCL11A,CNTNAP2,CSNK2A1,EPAS1,... 2251 unique
http://lsdb.hgu.mrc.ac.uk/ LOVD 2.0-30 11 genes 1903 variants
MRC Human Genetics Unit LOVD at MRC IGMM MLYCD,NIPBL,OTX2,PAX6,RAB18,RAB3GAP1,RAB3GAP2,RPGR,SMC1A,... 1111 unique
http://hci-exlovd.hci.utah.edu/ LOVD 2.0-22 3 genes 1822 variants
Database of BRCA1 and BRCA2 sequence variants that have been clinically reclassified using a quantit BRCA1,BRCA1fx,BRCA2 1850 unique
https://eds.gene.le.ac.uk/ LOVD 2.0-36 13 genes 1731 variants
Ehlers Danlos Syndrome Variant Database ADAMTS2,AEBP1,B3GALT6,B4GALT7,CHST14,COL3A1,COL5A1,COL5A2... 1072 unique
http://grenada.lumc.nl/LOVD2/VWF/ LOVD 2.0-37 1 gene 1728 variants
EAHAD Coagulation Factor Variant Databases VWF 713 unique
http://grenada.lumc.nl/LOVD2/TPI/ LOVD 2.0-37 9 genes 1127 variants
Parkinson's disease Mutation Database ATXN2,DNAJC13,GBA,LRRK2,PARK2,PARK7,PINK1,SNCA,VPS35 983 unique
http://dbpex.org/ LOVD 2.0-30 13 genes 1081 variants
dbPEX, PEX Gene Database PEX1,PEX10,PEX12,PEX13,PEX14,PEX16,PEX19,PEX2,PEX26,PEX3,... 389 unique
http://hgddatabase.cvtisr.sk/ LOVD 2.0-36 1 gene 1027 variants
HGD mutation database HGD 212 unique
http://mseqdr.lumc.edu/GEDI/ LOVD 3.0-08 298 genes 1012 variants
The Genetic Eye Disorder (GEDI) Variation Database ABCA4,ABCC6,ABHD12,ADAM9,ADAMTS18,AFG3L1P,AHI1,AIP,AIPL1,... 981 unique
http://mitodyn.org/ LOVD 2.0-36 2 genes 813 variants
MITOchondrial DYNamics variation pages GDAP1,OPA1 418 unique
http://143.169.238.105/LOVD/ LOVD 3.0-16 6 genes 713 variants
Loeys-Dietz Syndrome Mutation Database SMAD2,SMAD3,TGFB2,TGFB3,TGFBR1,TGFBR2 328 unique
https://coppolalab.ucla.edu/lovd_gift/ LOVD 3.0-21 11 genes 634 variants
Coppola Lab - GIFT Variant Database APP,C9orf72,CHMP2B,FUS,GRN,MAPT,PSEN1,PSEN2,TARDBP,TBK1,VCP 585 unique
https://grenada.lumc.nl/LOVD2/MD/ LOVD 2.0-37 1 gene 510 variants
Menkes Disease ATP7A 323 unique
http://www.dbagenes.unito.it/ LOVD 2.0-36 13 genes 399 variants
Diamond-Blackfan Anemia GATA1,RPL11,RPL15,RPL26,RPL31,RPL35A,RPL5,RPS10,RPS17,RPS... 256 unique
http://grenada.lumc.nl/LOVD2/WS/ LOVD 2.0-37 5 genes 368 variants
LOVD - Leiden Open Variation Database EDN3,EDNRB,MITF,PAX3,SOX10 291 unique
http://dna2.leeds.ac.uk/LOVD/ LOVD 3.0-13 19 genes 336 variants
LOVD - Leiden Open Variation Database ACPT,AMBN,AMELX,AMTN,C4orf26,COL17A1,DLX3,ENAM,FAM20A,FAM... 219 unique
https://grenada.lumc.nl/LOVD2/ARC/ LOVD 2.0-37 2 genes 333 variants
LOVD - Leiden Open Variation Database VIPAR,VPS33B 251 unique
http://80.211.174.221 LOVD 3.0-21 2 genes 301 variants
LOVD - Leiden Open Variation Database PKD1,PKD2 2 unique
http://grenada.lumc.nl/LOVD2/ROR/ LOVD 2.0-37 2 genes 291 variants
LOVD 2.0 - ROR genes ROR1,ROR2 55 unique
https://grenada.lumc.nl/LOVD2/PAX2/ LOVD 2.0-37 1 gene 263 variants
PAX2 variant database PAX2 92 unique
http://seqdb.parseq.pro/ LOVD 3.0-21 2 genes 226 variants
Консенсус по клиническим эффектам генетических вариа CFTR,PAH 223 unique
http://diabetes-insipidus.org/ LOVD 3.0-19 3 genes 213 variants
LOVD - Leiden Open Variation Database AQP2,AVP,AVPR2 131 unique
http://grenada.lumc.nl/LOVD2/ctx/ LOVD 2.0-37 1 gene 213 variants
Cerebrotendinous Xanthomatosis CYP27A1 69 unique
http://grenada.lumc.nl/LOVD2/mendelian_genes/ LOVD 2.0-37 2 genes 211 variants
Mendelian genes MFSD8,NOG 80 unique
https://lovd3.isciii.es/ LOVD 3.0-11 31 genes 188 variants
SpainMDB ABCD1,APC,ATP7B,BRAF,BRCA1,BRCA2,BSND,CFTR,CYP27A1,DMD,GH... 137 unique
https://drdb.gene.le.ac.uk/ LOVD 2.0-36 4 genes 184 variants
Death Receptor Database (DRdb) TNFRSF10A,TNFRSF10B,TNFRSF10C,TNFRSF10D 144 unique
http://bipmed.iqm.unicamp.br/BRCA-challenge/ LOVD 3.0-20 2 genes 180 variants
BRCA Challenge - BRAZIL BRCA1,BRCA2 158 unique
https://grenada.lumc.nl/LOVD2/uni-hd/5-HT/ LOVD 2.0-37 5 genes 170 variants
University of Heidelberg Serotonin receptor variant database HTR3A,HTR3B,HTR3C,HTR3D,HTR3E 73 unique
http://db.cshg.org.cy/ LOVD 3.0-17 44 genes 86 variants
APC,APCS,ATP6V1B1,BRCA1,BRCA2,C1QA,C1QC,CFH,CFHR5,CFTR,CO... 83 unique
http://www.genetik-regensburg.de/LOVDv.3.0/ LOVD 3.0-16 48 genes 76 variants
Labor Staber Humangenetik AIP,ATM,ATP7B,ATXN3,BLK,BRCA1,BRCA2,BRIP1,CDH1,CFTR,CHEK2... 74 unique
http://bipmed.iqm.unicamp.br/neurofibromatosis/ LOVD 3.0-21 2 genes 66 variants
BIPMed - Neurofibromatosis NF1,NF2 66 unique
http://bipmed.iqm.unicamp.br/deafness/ LOVD 3.0-21 13 genes 60 variants
Hereditary Hearing Loss Database CDH23,GJB2,GJB3,GJB6,MT-RNR1,MT-TA,MT-TK,MT-TS1,MT-TS2,MT... 59 unique
http://dna2.leeds.ac.uk/GRK1_LOVD/ LOVD 3.0-18 1 gene 59 variants
LOVD - Leiden Open Variation Database GRK1 23 unique
http://www.icp.ucl.ac.be/vikkula/CLPdb/ LOVD 2.0-36 1 gene 54 variants
Cleft Lip and Palate Mutation Database IRF6 44 unique
http://bipmed.iqm.unicamp.br/tuberous-sclerosis/ LOVD 3.0-17 2 genes 45 variants
BIPMed - Variants in tuberous sclerosis patients from Brazil TSC1,TSC2 44 unique
https://grenada.lumc.nl/LOVD2/TCS/ LOVD 2.0-37 2 genes 26 variants
Treacher Collins syndrome variant database POLR1C,POLR1D 22 unique
http://bipmed.iqm.unicamp.br/epileptic-encephalopathy/ LOVD 3.0-20 1 gene 16 variants
BIPMed - Epileptic Encephalopathy SCN1A 16 unique
http://genet.ir/variome/ LOVD 3.0-14 9063 genes 0 variants
Iran Variation Database A2M,A2ML1,A4GALT,AACS,AADACL2,AADAT,AAGAB,AAK1,AAR2,AARD,... 0 unique
http://grenada.lumc.nl/LOVD2/vumc/ LOVD 2.0-37 7 genes 0 variants
LOVD - Leiden Open Variation Database ALDH5A1,ASPA,D2HGDH,GAMT,GATM,L2HGDH,SLC6A8 0 unique
https://grenada.lumc.nl/LOVD2/CILD/ LOVD 2.0-37 5 genes 0 variants
Primary Ciliary Dyskinesia variant database DNAAF1,DNAH11,DNAH5,DNAI1,DNAI2 0 unique
http://bipmed.iqm.unicamp.br/gg2020/ LOVD 3.0-20 1 gene 0 variants
BIPMed - GG2020 - Beta thalassemia HBB 0 unique
http://l3.d-lohmann.de/ LOVD 3.0-18 1 gene 0 variants
Essen-Eye-Cancer-Genetics RB1 0 unique
http://grenada.lumc.nl/LOVD2/L1CAM/ LOVD 2.0-37 1 gene 0 variants
LOVD - Leiden Open Variation Database L1CAM 0 unique
http://chromium.lovd.nl/LOVD2/ LOVD 2.0-37 0 genes 0 variants
LOVD - Leiden Open Variation Database 0 unique
https://grenada.lumc.nl/LOVD2/CDG/ LOVD 2.0-37 0 genes 0 variants
Congenital disorders of glycosylation (CDG) 0 unique
http://bipmed.iqm.unicamp.br/lupus/ LOVD 3.0-21 0 genes 0 variants
BIPMed Lupus - HG38 0 unique
https://fogellab.neurology.ucla.edu/lovd/ LOVD 3.0-21 0 genes 0 variants
LOVD - Leiden Open Variation Database 0 unique
https://grenada.lumc.nl/LOVD2/NIH/eyegene/ LOVD 2.0-37 0 genes 0 variants
LOVD - Leiden Open Variation Database 0 unique
http://brca.iarc.fr/LOVD/ LOVD 2.0-22 ? genes ? variants
LOVD - IARC ? unique
(This list is updated daily and shows LOVD 2.0 and 3.0 installations active for the last three months that have the "include in the global LOVD listing" setting enabled. Please allow one day for changes to take effect.)

Last modified 2019/03/04 15:40:19 CET

When using or discussing LOVD please refer to:
Fokkema IF, Taschner PE, Schaafsma GC, Celli J, Laros JF, den Dunnen JT (2011). LOVD v.2.0: the next generation in gene variant databases. Hum Mutat. 2011 May;32(5):557-63.

A recommended system of the Human Variome Project LOVD has received funding from the European Community's Seventh Framework Programme
(FP7/2007-2013) under grant agreement nº 200754 - the GEN2PHEN project.
©2004-2019 Leiden University Medical Center, Netherlands
Ivo F.A.C. Fokkema BSc., Prof. Johan T. den Dunnen PhD
A IRDiRC recognized resource