List of public LOVD installations

Question If you are looking for a specific gene database, please also check our list of LSDBs.

Please note that the latest available build is always installed on our Leiden server. We offer free use of this LOVD installation for those interested, e.g. to maintain/start a LSDB. Contact us for more information.

Show only LOVDs with gene symbol:

You can also download this list to see the complete list of genes in the databases.

In total: 292,517,013 variants (3,953,589 unique) in 904,142 individuals in 81 LOVD installations.
http://bipmed.iqm.unicamp.br/snparray/ LOVD 3.0-20 17391 genes 222715116 variants
BIPMed SNP Array A1BG-AS1,A1CF,A2M,A2M-AS1,A2ML1,A2MP1,A3GALT2,A4GALT,A4GN... 902273 unique
http://bipmed.iqm.unicamp.br/ LOVD 3.0-21 20930 genes 66158522 variants
BIPMed WES A1BG,A1BG-AS1,A1CF,A2M,A2M-AS1,A2ML1,A2MP1,A3GALT2,A4GALT... 622610 unique
http://databases.lovd.nl/whole_genome/ LOVD 3.0-20a 22002 genes 1998175 variants
Whole genome datasets A1BG,A1BG-AS1,A1CF,A2M,A2M-AS1,A2ML1,A2MP1,A4GALT,A4GNT,A... 1998135 unique
https://databases.lovd.nl/shared/ LOVD 3.0-21 22980 genes 890949 variants
Global Variome shared LOVD A1BG,A1BG-AS1,A1CF,A2LD1,A2M,A2M-AS1,A2ML1,A2MP1,A3GALT2,... 174038 unique
http://proteomics.bio21.unimelb.edu.au/lovd/ LOVD 3.0-07 14772 genes 239690 variants
LOVD - Leiden Open Variation Database A1BG,A1BG-AS1,A1CF,A2M,A2ML1,A4GALT,A4GNT,AAAS,AACS,AACSP... 152241 unique
http://bipmed.iqm.unicamp.br/cfa/ LOVD 3.0-21 41 genes 134333 variants
Craniofacial anomalies APOC2,APOC4-APOC2,AXIN2,BCL3,BMP4,CLPTM1,DVL2,ERBB2,FGF22... 257 unique
https://ab-openlab.csir.res.in/mitolsdb/ LOVD 2.0-35 37 genes 112662 variants
MitoLSDB MTATP6,MTATP8,MTCO1,MTCO2,MTCO3,MTCYB,MTND1,MTND2,MTND3,M... 4660 unique
http://www.insight-database.org/ LOVD 3.0-21 17 genes 36832 variants
International Society for Gastrointestinal Hereditary Tumours Database APC,BMPR1A,EPCAM,FBXO11,GALNT12,MLH1,MLH3,MSH2,MSH3,MSH6,... 5841 unique
http://HCI-LOVD.hci.utah.edu LOVD 2.0-33 8 genes 26167 variants
LOVD - human mismatch repair genes MLH1,MLH1_priors,MSH2,MSH2_priors,MSH6,MSH6_priors,PMS2,P... 26167 unique
http://grenada.lumc.nl/LOVD2/mendelian_genes/ LOVD 2.0-36 188 genes 25999 variants
Mendelian genes ABO,ACTB,ACTG1,ACVR1,ADA,ADAMTS13,ADAMTSL2,AGL,AGPAT2,AGP... 4738 unique
https://grenada.lumc.nl/LOVD2/Usher_montpellier/ LOVD 2.0-36 20 genes 23521 variants
Retinal and hearing impairment genetic mutation database CDH23,CEACAM16,CERKL,CHM,CLDN14,CLRN1,GPR98,MYO15A,MYO6,M... 3656 unique
http://www.dmd.nl/nmdb2/ LOVD 2.0-36 55 genes 21256 variants
Leiden Muscular Dystrophy pages ANKRD1,BAG3,CAPN3,CHAT,CHKB,COLQ,CRYAB,DAG1,DES,DNAJB6,DO... 5079 unique
http://grenada.lumc.nl/LOVD2/MR/ LOVD 2.0-36 426 genes 20575 variants
X-chromosome gene database ACOT9,ACSL4,ACTRT1,AFF2,AGTR2,AKAP14,AKAP4,ALG13,AMELX,AM... 1429 unique
http://chromium.lovd.nl/LOVD2/TSC/ LOVD 2.0-36 2 genes 20314 variants
Tuberous sclerosis database TSC1,TSC2 3972 unique
http://www.genomed.org/lovd2/ LOVD 2.0-35 111 genes 16073 variants
Zhejiang University Center for Genetic and Genomic Medicine (ZJU-CGGM) ABCC9,ACTC1,ACTN2,AKAP9,ANK2,APC,AXIN2,BARD1,BCL11A,BRCA1... 10206 unique
https://mseqdr.org/MITO/ LOVD 3.0-21 1607 genes 14002 variants
MSeqDR-LSDB Mitochondrial Disease Locus Specific Database AADAT,AARS2,AASS,ABAT,ABCA13,ABCA9,ABCB10,ABCB6,ABCB7,ABC... 11810 unique
http://grenada.lumc.nl/LOVD2/diabetes/ LOVD 2.0-36 3 genes 9791 variants
Monogenic Diabetes GCK,HNF1A,HNF4A 691 unique
http://bioinf.suda.edu.cn/NDDvarbase/LOVDv.3.0/ LOVD 3.0-13 289 genes 6374 variants
NDDVD - Neurodegenerative Diseases Variation Database ABCA7,ABCB1,ADCY5,ADORA1,ADRA1A,AFG3L2,AGBL3,ALS2,ANG,ANK... 4959 unique
http://inc.msal.gov.ar/lovd-prueba-V3.18-07062017/ LOVD 3.0-19 40 genes 4801 variants
SITHER APC,ATM,BAP1,BARD1,BMPR1A,BRCA1,BRCA2,BRIP1,CDH1,CDK4,CDK... 507 unique
https://oi.gene.le.ac.uk/ LOVD 2.0-36 20 genes 3925 variants
Osteogenesis Imperfecta Variant Database BMP1,COL1A1,COL1A2,CREB3L1,CRTAP,FAM46A,FKBP10,IFITM5,P3H... 1966 unique
https://lovd.euro-wabb.org/ LOVD 2.0-36 23 genes 3578 variants
EURO-WABB PROJECT OPEN VARIATION DATABASE ALMS1,ARL6,BBIP1,BBS1,BBS10,BBS12,BBS2,BBS4,BBS5,BBS7,BBS... 1131 unique
http://databases.lovd.nl/DNA_profiles/ LOVD 3.0-20a 0 genes 3414 variants
LOVD - Leiden Open Variation Database 667 unique
http://rb1-lovd.d-lohmann.de/ LOVD 2.0-34 1 gene 3395 variants
rb1-lsdb RB1 1752 unique
http://grenada.lumc.nl/LOVD2/vumc/ LOVD 2.0-36 7 genes 3008 variants
LOVD - Leiden Open Variation Database ALDH5A1,ASPA,D2HGDH,GAMT,GATM,L2HGDH,SLC6A8 636 unique
http://lovd.bx.psu.edu/ LOVD 2.0-36 37 genes 2286 variants
The Globin Gene Server ALOX5AP,AQP9,ARG2,ASS1,ATRX,BCL11A,CNTNAP2,CSNK2A1,EPAS1,... 2227 unique
http://grenada.lumc.nl/LOVD2/VWF/ LOVD 2.0-36 2 genes 2151 variants
EAHAD Coagulation Factor Variant Databases GP1BA,VWF 739 unique
http://lsdb.hgu.mrc.ac.uk/ LOVD 2.0-30 11 genes 1903 variants
MRC Human Genetics Unit LOVD at MRC IGMM MLYCD,NIPBL,OTX2,PAX6,RAB18,RAB3GAP1,RAB3GAP2,RPGR,SMC1A,... 1111 unique
https://eds.gene.le.ac.uk/ LOVD 2.0-36 13 genes 1696 variants
Ehlers Danlos Syndrome Variant Database ADAMTS2,AEBP1,B3GALT6,B4GALT7,CHST14,COL3A1,COL5A1,COL5A2... 1049 unique
http://grenada.lumc.nl/LOVD2/ARVC/ LOVD 2.0-36 8 genes 1555 variants
ARVD/C Genetic Variants Database DSC2,DSG2,DSP,JUP,PKP2,TGFB3,TMEM43,TP63 1027 unique
http://secure.ngrl.org.uk/LOVDv.2.0/ LOVD 2.0-28 5 genes 1404 variants
NGRL, Manchester LOVD CHM,KDM6A,L1CAM,MLL2,UBE3A 540 unique
http://databases.lovd.ni/shared/ LOVD 3.0-14 11 genes 1312 variants
LOVD - Leiden Open Variation Database APC,CCND1,CXCL8,KRAS,MLH1,MSH2,MSH6,NFKB1,NFKBIA,PMS2,TP53 55 unique
http://grenada.lumc.nl/LOVD2/TPI/ LOVD 2.0-36 9 genes 1127 variants
Parkinson's disease Mutation Database ATXN2,DNAJC13,GBA,LRRK2,PARK2,PARK7,PINK1,SNCA,VPS35 983 unique
http://dbpex.org/ LOVD 2.0-30 13 genes 1081 variants
dbPEX, PEX Gene Database PEX1,PEX10,PEX12,PEX13,PEX14,PEX16,PEX19,PEX2,PEX26,PEX3,... 389 unique
http://mseqdr.lumc.edu/GEDI/ LOVD 3.0-08 298 genes 1012 variants
The Genetic Eye Disorder (GEDI) Variation Database ABCA4,ABCC6,ABHD12,ADAM9,ADAMTS18,AFG3L1P,AHI1,AIP,AIPL1,... 981 unique
http://hgddatabase.cvtisr.sk/ LOVD 2.0-36 1 gene 842 variants
HGD mutation database HGD 203 unique
http://mitodyn.org/ LOVD 2.0-36 2 genes 813 variants
MITOchondrial DYNamics variation pages GDAP1,OPA1 418 unique
http://143.169.238.105/LOVD/ LOVD 3.0-16 6 genes 713 variants
Loeys-Dietz Syndrome Mutation Database SMAD2,SMAD3,TGFB2,TGFB3,TGFBR1,TGFBR2 328 unique
http://hci-exlovd.hci.utah.edu/ LOVD 2.0-22 3 genes 659 variants
Database of BRCA1 and BRCA2 sequence variants that have been clinically reclassified using a quantit BRCA1,BRCA1fx,BRCA2 512 unique
https://coppolalab.ucla.edu/lovd_gift/ LOVD 3.0-19 11 genes 634 variants
Coppola Lab - GIFT Variant Database APP,C9orf72,CHMP2B,FUS,GRN,MAPT,PSEN1,PSEN2,TARDBP,TBK1,VCP 585 unique
https://grenada.lumc.nl/LOVD2/MD/ LOVD 2.0-36 1 gene 510 variants
Menkes Disease ATP7A 323 unique
http://grenada.lumc.nl/LOVD2/FHM/ LOVD 2.0-36 3 genes 500 variants
Familial Hemiplegic Migraine (FHM) Variation Database ATP1A2,CACNA1A,SCN1A 143 unique
http://www.dbagenes.unito.it/ LOVD 2.0-36 13 genes 399 variants
Diamond-Blackfan Anemia GATA1,RPL11,RPL15,RPL26,RPL31,RPL35A,RPL5,RPS10,RPS17,RPS... 256 unique
http://grenada.lumc.nl/LOVD2/WS/ LOVD 2.0-36 5 genes 368 variants
LOVD - Leiden Open Variation Database EDN3,EDNRB,MITF,PAX3,SOX10 291 unique
https://grenada.lumc.nl/LOVD2/ARC/ LOVD 2.0-36 2 genes 333 variants
LOVD - Leiden Open Variation Database VIPAR,VPS33B 251 unique
http://dna2.leeds.ac.uk/LOVD/ LOVD 3.0-13 18 genes 307 variants
LOVD - Leiden Open Variation Database ACPT,AMBN,AMELX,AMTN,C4orf26,COL17A1,DLX3,ENAM,FAM20A,FAM... 198 unique
http://grenada.lumc.nl/LOVD2/ROR/ LOVD 2.0-36 2 genes 291 variants
LOVD 2.0 - ROR genes ROR1,ROR2 55 unique
http://80.211.174.221 LOVD 3.0-21 2 genes 278 variants
LOVD - Leiden Open Variation Database PKD1,PKD2 2 unique
https://grenada.lumc.nl/LOVD2/PAX2/ LOVD 2.0-36 1 gene 263 variants
PAX2 variant database PAX2 92 unique
http://diabetes-insipidus.org/ LOVD 3.0-19 3 genes 213 variants
LOVD - Leiden Open Variation Database AQP2,AVP,AVPR2 131 unique
http://grenada.lumc.nl/LOVD2/ctx/ LOVD 2.0-36 1 gene 213 variants
Cerebrotendinous Xanthomatosis CYP27A1 69 unique
https://lovd3.isciii.es/ LOVD 3.0-11 31 genes 188 variants
SpainMDB ABCD1,APC,ATP7B,BRAF,BRCA1,BRCA2,BSND,CFTR,CYP27A1,DMD,GH... 137 unique
https://grenada.lumc.nl/LOVD2/NIH/eyegene/ LOVD 2.0-36 4 genes 186 variants
LOVD - Leiden Open Variation Database CHM,PRPF8,RB1,RHO 73 unique
https://drdb.gene.le.ac.uk/ LOVD 2.0-36 4 genes 184 variants
Death Receptor Database (DRdb) TNFRSF10A,TNFRSF10B,TNFRSF10C,TNFRSF10D 144 unique
http://bipmed.iqm.unicamp.br/BRCA-challenge/ LOVD 3.0-20 2 genes 180 variants
BRCA Challenge - BRAZIL BRCA1,BRCA2 158 unique
http://grenada.lumc.nl/LOVD2/amc/ LOVD 2.0-36 1 gene 171 variants
LOVD - Leiden Open Variation Database PORCN 119 unique
https://grenada.lumc.nl/LOVD2/uni-hd/5-HT/ LOVD 2.0-36 5 genes 170 variants
University of Heidelberg Serotonin receptor variant database HTR3A,HTR3B,HTR3C,HTR3D,HTR3E 73 unique
http://db.cshg.org.cy/ LOVD 3.0-17 44 genes 86 variants
APC,APCS,ATP6V1B1,BRCA1,BRCA2,C1QA,C1QC,CFH,CFHR5,CFTR,CO... 83 unique
http://sysbio.org.cn LOVD 2.0-33 1 gene 80 variants
Alexander disease_NDDMD GFAP 70 unique
http://bipmed.iqm.unicamp.br/neurofibromatosis/ LOVD 3.0-21 2 genes 66 variants
BIPMed - Neurofibromatosis NF1,NF2 66 unique
http://bipmed.iqm.unicamp.br/deafness/ LOVD 3.0-21 13 genes 60 variants
Hereditary Hearing Loss Database CDH23,GJB2,GJB3,GJB6,MT-RNR1,MT-TA,MT-TK,MT-TS1,MT-TS2,MT... 59 unique
http://dna2.leeds.ac.uk/GRK1_LOVD/ LOVD 3.0-18 1 gene 59 variants
LOVD - Leiden Open Variation Database GRK1 23 unique
http://www.icp.ucl.ac.be/vikkula/CLPdb/ LOVD 2.0-36 1 gene 54 variants
Cleft Lip and Palate Mutation Database IRF6 44 unique
http://bipmed.iqm.unicamp.br/tuberous-sclerosis/ LOVD 3.0-17 2 genes 45 variants
BIPMed - Variants in tuberous sclerosis patients from Brazil TSC1,TSC2 44 unique
http://databases.locd.nl/shared/ LOVD 3.0-13 3 genes 43 variants
National Thalassemia Database HBA1,HBA2,HBB 24 unique
http://www.genetik-regensburg.de/LOVDv.3.0/ LOVD 3.0-16 38 genes 34 variants
Labor Staber Humangenetik AIP,ATM,ATP7B,ATXN3,BRCA1,BRCA2,CFTR,CHEK2,CPA1,CYP21A2,E... 33 unique
http://ibio-cn.org LOVD 2.0-31 1 gene 30 variants
Canavan Disease_NDDMD ASPA 22 unique
https://grenada.lumc.nl/LOVD2/TCS/ LOVD 2.0-36 2 genes 26 variants
Treacher Collins syndrome variant database POLR1C,POLR1D 22 unique
http://bipmed.iqm.unicamp.br/epileptic-encephalopathy/ LOVD 3.0-20 1 gene 16 variants
BIPMed - Epileptic Encephalopathy SCN1A 16 unique
http://genet.ir/variome/ LOVD 3.0-14 9063 genes 0 variants
Iran Variation Database A2M,A2ML1,A4GALT,AACS,AADACL2,AADAT,AAGAB,AAK1,AAR2,AARD,... 0 unique
https://grenada.lumc.nl/LOVD2/CILD/ LOVD 2.0-36 5 genes 0 variants
Primary Ciliary Dyskinesia variant database DNAAF1,DNAH11,DNAH5,DNAI1,DNAI2 0 unique
http://bipmed.iqm.unicamp.br/gg2020/ LOVD 3.0-20 1 gene 0 variants
BIPMed - GG2020 - Beta thalassemia HBB 0 unique
http://grenada.lumc.nl/LOVD2/L1CAM/ LOVD 2.0-36 1 gene 0 variants
LOVD - Leiden Open Variation Database L1CAM 0 unique
http://l3.d-lohmann.de/ LOVD 3.0-18 1 gene 0 variants
Essen-Eye-Cancer-Genetics RB1 0 unique
http://chromium.lovd.nl/LOVD2/ LOVD 2.0-36 0 genes 0 variants
LOVD - Leiden Open Variation Database 0 unique
http://lovd.urugenomes.org/ LOVD 3.0-21 0 genes 0 variants
LOVD - Urugenomes 0 unique
https://grenada.lumc.nl/LOVD2/CDG/ LOVD 2.0-36 0 genes 0 variants
Congenital disorders of glycosylation (CDG) 0 unique
http://clinbiodb2015.univ-angers.fr/LOVDv.3.0/ LOVD 3.0-13 0 genes 0 variants
#clinbiodb2015 0 unique
http://grenada.lumc.nl/LOVD2/CDLS/ LOVD 2.0-36 0 genes 0 variants
LOVD - Leiden Open Variation Database 0 unique
https://fogellab.neurology.ucla.edu/lovd/ LOVD 3.0-21 0 genes 0 variants
LOVD - Leiden Open Variation Database 0 unique
http://databases.lovd.nl/shared/ LOVD 3.0-19 0 genes 0 variants
LOVD - Leiden Open Variation Database 0 unique
http://brca.iarc.fr/LOVD/ LOVD 2.0-22 ? genes ? variants
LOVD - IARC ? unique
(This list is updated daily and shows LOVD 2.0 and 3.0 installations active for the last three months that have the "include in the global LOVD listing" setting enabled. Please allow one day for changes to take effect. Also, known 1.1.0 installations have been added.)

Last modified 2017/07/24 14:23:43 CEST

When using or discussing LOVD please refer to:
Fokkema IF, Taschner PE, Schaafsma GC, Celli J, Laros JF, den Dunnen JT (2011). LOVD v.2.0: the next generation in gene variant databases. Hum Mutat. 2011 May;32(5):557-63.

A recommended system of the Human Variome Project LOVD has received funding from the European Community's Seventh Framework Programme
(FP7/2007-2013) under grant agreement nº 200754 - the GEN2PHEN project.
©2004-2018 Leiden University Medical Center, Netherlands
Ivo F.A.C. Fokkema BSc., Prof. Johan T. den Dunnen PhD