List of public LOVD installations

If you are looking for a specific gene database, please also check our list of LSDBs.

Leiden server

download this list

In total: 3,777,386 variants (2,942,107 unique) in 422,029 individuals in 85 LOVD installations.

http://databases.lovd.nl/whole_genome/

LOVD 3.0-20a

22002 genes

1998175 variants

Whole genome datasets

A1BG,A1BG-AS1,A1CF,A2M,A2M-AS1,A2ML1,A2MP1,A4GALT,A4GNT,A...

1998135 unique

http://bipmed.iqm.unicamp.br/

LOVD 3.0-17

20930 genes

624137 variants

BIPMed WES

A1BG,A1BG-AS1,A1CF,A2M,A2M-AS1,A2ML1,A2MP1,A3GALT2,A4GALT...

622610 unique

https://databases.lovd.nl/shared/

LOVD 3.0-20a

22977 genes

523504 variants

Shared database

A1BG,A1BG-AS1,A1CF,A2LD1,A2M,A2M-AS1,A2ML1,A2MP1,A3GALT2,...

73608 unique

http://proteomics.bio21.unimelb.edu.au/lovd/

LOVD 3.0-07

14772 genes

239690 variants

LOVD - Leiden Open Variation Database

A1BG,A1BG-AS1,A1CF,A2M,A2ML1,A4GALT,A4GNT,AAAS,AACS,AACSP...

152241 unique

https://ab-openlab.csir.res.in/mitolsdb/

LOVD 2.0-35

37 genes

112662 variants

MitoLSDB

MTATP6,MTATP8,MTCO1,MTCO2,MTCO3,MTCYB,MTND1,MTND2,MTND3,M...

4660 unique

http://www.dmd.nl/nmdb2/

LOVD 2.0-36

101 genes

45985 variants

Leiden Muscular Dystrophy pages

ANKRD1,B3GNT1,BAG3,BANF1,BIN1,CAPN3,CFL2,CHAT,CHKB,CHRNA1...

8209 unique

http://grenada.lumc.nl/LOVD2/mendelian_genes/

LOVD 2.0-36

203 genes

26754 variants

Mendelian genes

ABO,ACTB,ACTG1,ACVR1,ADA,ADAMTS13,ADAMTSL2,AGL,AGPAT2,AGP...

5110 unique

http://HCI-LOVD.hci.utah.edu

LOVD 2.0-33

8 genes

26167 variants

LOVD - human mismatch repair genes

MLH1,MLH1_priors,MSH2,MSH2_priors,MSH6,MSH6_priors,PMS2,P...

26167 unique

http://chromium.lovd.nl/LOVD2/colon_cancer/

LOVD 2.0-36

9 genes

25621 variants

Colon cancer gene variant databases

APC,CDH1,GALNT12,MLH1,MLH3,MSH2,MSH6,MUTYH,PMS2

3434 unique

https://grenada.lumc.nl/LOVD2/Usher_montpellier/

LOVD 2.0-36

20 genes

23483 variants

Retinal and hearing impairment genetic mutation database

CDH23,CEACAM16,CERKL,CHM,CLDN14,CLRN1,GPR98,MYO15A,MYO6,M...

3647 unique

http://grenada.lumc.nl/LOVD2/MR/

LOVD 2.0-36

427 genes

20579 variants

X-chromosome gene database

ACOT9,ACSL4,ACTRT1,AFF2,AGTR2,AKAP14,AKAP4,ALG13,AMELX,AM...

1431 unique

http://chromium.lovd.nl/LOVD2/TSC/

LOVD 2.0-36

2 genes

19317 variants

Tuberous sclerosis database

TSC1,TSC2

3766 unique

http://www.insight-database.org/

LOVD 3.0-19

14 genes

16555 variants

International Society for Gastrointestinal Hereditary Tumours Database

APC,EPCAM,FBXO11,MLH1,MLH3,MSH2,MSH3,MSH6,MUTYH,PALB2,PMS...

3438 unique

http://www.genomed.org/lovd2/

LOVD 2.0-35

96 genes

15133 variants

Zhejiang University Center for Genetic and Genomic Medicine (ZJU-CGGM)

ABCC9,ACTC1,ACTN2,AKAP9,ANK2,APC,AXIN2,BARD1,BRCA1,BRCA2,...

9327 unique

http://grenada.lumc.nl/LOVD2/diabetes/

LOVD 2.0-36

3 genes

9783 variants

Monogenic Diabetes

GCK,HNF1A,HNF4A

690 unique

http://bioinf.suda.edu.cn/NDDvarbase/LOVDv.3.0/

LOVD 3.0-13

226 genes

5946 variants

NDDVD - Neurodegenerative Diseases Variation Database

ABCA7,ADCY5,ADORA1,AFG3L2,AGBL3,ALS2,ANG,APEX1,APOA1,APOE...

4678 unique

https://oi.gene.le.ac.uk/

LOVD 2.0-36

19 genes

3733 variants

Osteogenesis Imperfecta Variant Database

BMP1,COL1A1,COL1A2,CREB3L1,CRTAP,FKBP10,IFITM5,P3H1,P4HB,...

1891 unique

https://lovd.euro-wabb.org/

LOVD 2.0-36

23 genes

3560 variants

EURO-WABB PROJECT OPEN VARIATION DATABASE

ALMS1,ARL6,BBIP1,BBS1,BBS10,BBS12,BBS2,BBS4,BBS5,BBS7,BBS...

1122 unique

http://databases.lovd.nl/DNA_profiles/

LOVD 3.0-20

0 genes

3414 variants

LOVD - Leiden Open Variation Database

667 unique

http://rb1-lovd.d-lohmann.de/

LOVD 2.0-34

1 gene

3390 variants

rb1-lsdb

RB1

1748 unique

http://grenada.lumc.nl/LOVD2/vumc/

LOVD 2.0-36

7 genes

2980 variants

LOVD - Leiden Open Variation Database

ALDH5A1,ASPA,D2HGDH,GAMT,GATM,L2HGDH,SLC6A8

617 unique

http://lovd.bx.psu.edu/

LOVD 2.0-36

37 genes

2240 variants

The Globin Gene Server

ALOX5AP,AQP9,ARG2,ASS1,ATRX,BCL11A,CNTNAP2,CSNK2A1,EPAS1,...

2182 unique

http://grenada.lumc.nl/LOVD2/VWF/

LOVD 2.0-36

2 genes

2151 variants

EAHAD Coagulation Factor Variant Databases

GP1BA,VWF

739 unique

http://lsdb.hgu.mrc.ac.uk/

LOVD 2.0-30

11 genes

1862 variants

MRC Human Genetics Unit LOVD at MRC IGMM

MLYCD,NIPBL,OTX2,PAX6,RAB18,RAB3GAP1,RAB3GAP2,RPGR,SMC1A,...

1092 unique

https://eds.gene.le.ac.uk/

LOVD 2.0-36

12 genes

1637 variants

Ehlers Danlos Syndrome Variant Database

ADAMTS2,B3GALT6,B4GALT7,CHST14,COL3A1,COL5A1,COL5A2,DSE,F...

1008 unique

http://grenada.lumc.nl/LOVD2/ARVC/

LOVD 2.0-36

8 genes

1555 variants

ARVD/C Genetic Variants Database

DSC2,DSG2,DSP,JUP,PKP2,TGFB3,TMEM43,TP63

1027 unique

http://grenada.lumc.nl/LOVD2/CDLS/

LOVD 2.0-36

5 genes

1512 variants

LOVD - Leiden Open Variation Database

NIPBL,PDS5A,PDS5B,SMC1A,SMC3

366 unique

http://secure.ngrl.org.uk/LOVDv.2.0/

LOVD 2.0-28

5 genes

1404 variants

NGRL, Manchester LOVD

CHM,KDM6A,L1CAM,MLL2,UBE3A

540 unique

http://databases.lovd.ni/shared/

LOVD 3.0-14

11 genes

1312 variants

LOVD - Leiden Open Variation Database

APC,CCND1,CXCL8,KRAS,MLH1,MSH2,MSH6,NFKB1,NFKBIA,PMS2,TP53

55 unique

http://grenada.lumc.nl/LOVD2/TPI/

LOVD 2.0-36

9 genes

1127 variants

Parkinson's disease Mutation Database

ATXN2,DNAJC13,GBA,LRRK2,PARK2,PARK7,PINK1,SNCA,VPS35

983 unique

http://medgen.ua.ac.be/LOVDv.2.0/

LOVD 2.0-33

2 genes

1110 variants

Multiple Osteochondroma Mutation Database

EXT1,EXT2

663 unique

http://www.dbpex.org/

LOVD 2.0-30

13 genes

1081 variants

dbPEX, PEX Gene Database

PEX1,PEX10,PEX12,PEX13,PEX14,PEX16,PEX19,PEX2,PEX26,PEX3,...

389 unique

http://mseqdr.lumc.edu/GEDI/

LOVD 3.0-08

298 genes

1012 variants

The Genetic Eye Disorder (GEDI) Variation Database

ABCA4,ABCC6,ABHD12,ADAM9,ADAMTS18,AFG3L1P,AHI1,AIP,AIPL1,...

981 unique

http://hgddatabase.cvtisr.sk/

LOVD 2.0-36

1 gene

826 variants

HGD mutation database

HGD

203 unique

http://mitodyn.org/

LOVD 2.0-36

2 genes

813 variants

MITOchondrial DYNamics variation pages

GDAP1,OPA1

418 unique

http://hci-exlovd.hci.utah.edu/

LOVD 2.0-22

3 genes

659 variants

Database of BRCA1 and BRCA2 sequence variants that have been clinically reclassified using a quantit

BRCA1,BRCA1fx,BRCA2

512 unique

https://grenada.lumc.nl/LOVD2/MD/

LOVD 2.0-36

1 gene

510 variants

Menkes Disease

ATP7A

323 unique

http://grenada.lumc.nl/LOVD2/FHM/

LOVD 2.0-36

3 genes

500 variants

Familial Hemiplegic Migraine (FHM) Variation Database

ATP1A2,CACNA1A,SCN1A

143 unique

http://medgen.ua.ac.be/LOVDv.3.0/

LOVD 3.0-16

6 genes

488 variants

LOVD - Leiden Open Variation Database

SMAD2,SMAD3,TGFB2,TGFB3,TGFBR1,TGFBR2

204 unique

https://coppolalab.ucla.edu/lovd_gift/

LOVD 3.0-19

5 genes

485 variants

Coppola Lab - GIFT Variant Database

APP,GRN,MAPT,PSEN1,PSEN2

436 unique

http://www.dbagenes.unito.it/

LOVD 2.0-36

13 genes

397 variants

Diamond-Blackfan Anemia

GATA1,RPL11,RPL15,RPL26,RPL31,RPL35A,RPL5,RPS10,RPS17,RPS...

254 unique

http://www-huge.uni-regensburg.de/BEST1_database/

LOVD 2.0-23

1 gene

394 variants

Bestrophin 1 (BEST1)

BEST1

269 unique

http://grenada.lumc.nl/LOVD2/WS/

LOVD 2.0-36

5 genes

368 variants

LOVD - Leiden Open Variation Database

EDN3,EDNRB,MITF,PAX3,SOX10

291 unique

https://grenada.lumc.nl/LOVD2/ARC/

LOVD 2.0-36

2 genes

333 variants

LOVD - Leiden Open Variation Database

VIPAR,VPS33B

251 unique

http://dna2.leeds.ac.uk/LOVD/

LOVD 3.0-13

18 genes

296 variants

LOVD - Leiden Open Variation Database

ACPT,AMBN,AMELX,AMTN,C4orf26,COL17A1,DLX3,ENAM,FAM20A,FAM...

193 unique

http://grenada.lumc.nl/LOVD2/ROR/

LOVD 2.0-36

2 genes

291 variants

LOVD 2.0 - ROR genes

ROR1,ROR2

55 unique

http://www.icp.ucl.ac.be/vikkula/VAdb/

LOVD 2.0-36

16 genes

248 variants

Vascular Anomaly and Lymphedema Mutation Database

CCBE1,CCM2,FLT4,FOXC2,GATA2,GJC2,GLMN,IDH1,IDH2,KIF11,KRI...

168 unique

https://grenada.lumc.nl/LOVD2/PAX2/

LOVD 2.0-36

1 gene

248 variants

PAX2 variant database

PAX2

83 unique

http://ec2-52-59-113-2.eu-central-1.compute.amazonaws.com/LOVD/

LOVD 3.0-16

2 genes

214 variants

LOVD - Leiden Open Variation Database

PKD1,PKD2

1 unique

http://grenada.lumc.nl/LOVD2/ctx/

LOVD 2.0-36

1 gene

213 variants

Cerebrotendinous Xanthomatosis

CYP27A1

69 unique

https://lovd3.isciii.es/

LOVD 3.0-11

31 genes

188 variants

SpainMDB

ABCD1,APC,ATP7B,BRAF,BRCA1,BRCA2,BSND,CFTR,CYP27A1,DMD,GH...

137 unique

https://grenada.lumc.nl/LOVD2/NIH/eyegene/

LOVD 2.0-36

4 genes

186 variants

LOVD - Leiden Open Variation Database

CHM,PRPF8,RB1,RHO

73 unique

https://drdb.gene.le.ac.uk/

LOVD 2.0-36

4 genes

184 variants

Death Receptor Database (DRdb)

TNFRSF10A,TNFRSF10B,TNFRSF10C,TNFRSF10D

144 unique

http://grenada.lumc.nl/LOVD2/amc/

LOVD 2.0-36

1 gene

171 variants

LOVD - Leiden Open Variation Database

PORCN

119 unique

https://grenada.lumc.nl/LOVD2/uni-hd/5-HT/

LOVD 2.0-36

5 genes

170 variants

University of Heidelberg Serotonin receptor variant database

HTR3A,HTR3B,HTR3C,HTR3D,HTR3E

73 unique

http://nndimontreal.ca/lovd3/

LOVD 3.0-19

1 gene

115 variants

LOVD - Leiden Open Variation Database

AVP

68 unique

http://server.goldenhelix.org/a1atvar/

LOVD 2.0-30

1 gene

94 variants

a1atvar

SERPINA1

66 unique

http://db.cshg.org.cy/

LOVD 3.0-17

44 genes

86 variants

APC,APCS,ATP6V1B1,BRCA1,BRCA2,C1QA,C1QC,CFH,CFHR5,CFTR,CO...

83 unique

http://sysbio.org.cn

LOVD 2.0-33

1 gene

80 variants

Alexander disease_NDDMD

GFAP

70 unique

http://dna2.leeds.ac.uk/GRK1_LOVD/

LOVD 3.0-18

1 gene

59 variants

LOVD - Leiden Open Variation Database

GRK1

23 unique

http://www.icp.ucl.ac.be/vikkula/CLPdb/

LOVD 2.0-36

1 gene

54 variants

Cleft Lip and Palate Mutation Database

IRF6

44 unique

http://databases.locd.nl/shared/

LOVD 3.0-13

3 genes

43 variants

National Thalassemia Database

HBA1,HBA2,HBB

24 unique

http://ibio-cn.org

LOVD 2.0-31

1 gene

30 variants

Canavan Disease_NDDMD

ASPA

22 unique

http://www.genetik-regensburg.de/LOVDv.3.0/

LOVD 3.0-16

37 genes

29 variants

MVZ Dr. Staber & Kollegen Regensburg, Germany

AIP,ATM,ATP7B,ATXN3,BRCA1,BRCA2,CFTR,CHEK2,CYP21A2,ERCC3,...

28 unique

https://grenada.lumc.nl/LOVD2/TCS/

LOVD 2.0-36

2 genes

26 variants

Treacher Collins syndrome variant database

POLR1C,POLR1D

22 unique

http://bipmed.iqm.unicamp.br/epileptic-encephalopathy/

LOVD 3.0-19

1 gene

16 variants

BIPMed - Epileptic Encephalopathy

SCN1A

16 unique

http://www.medgen.mcgill.ca/ANO5/

LOVD 2.0-24

1 gene

1 variants

ANO5 LOVD - Leiden Open Variation Database

ANO5

1 unique

http://genet.ir/variome/

LOVD 3.0-14

9063 genes

0 variants

Iran Variation Database

A2M,A2ML1,A4GALT,AACS,AADACL2,AADAT,AAGAB,AAK1,AAR2,AARD,...

0 unique

http://bipmed.iqm.unicamp.br/cfa/

LOVD 3.0-17

41 genes

0 variants

Brazilian Database on Craniofacial Anomalies

APOC2,APOC4-APOC2,AXIN2,BCL3,BMP4,CLPTM1,DVL2,ERBB2,FGF22...

0 unique

https://grenada.lumc.nl/LOVD2/CILD/

LOVD 2.0-36

5 genes

0 variants

Primary Ciliary Dyskinesia variant database

DNAAF1,DNAH11,DNAH5,DNAI1,DNAI2

0 unique

http://bipmed.iqm.unicamp.br/tuberous-sclerosis/

LOVD 3.0-17

3 genes

0 variants

BIPMed - Variants in tuberous sclerosis patients from Brazil

PKD1,TSC1,TSC2

0 unique

http://bipmed.iqm.unicamp.br/BRCA-challenge/

LOVD 3.0-19

2 genes

0 variants

BRCA Challenge - BRAZIL

BRCA1,BRCA2

0 unique

http://l3.d-lohmann.de/

LOVD 3.0-18

1 gene

0 variants

Essen-Eye-Cancer-Genetics

RB1

0 unique

http://grenada.lumc.nl/LOVD2/L1CAM/

LOVD 2.0-36

1 gene

0 variants

LOVD - Leiden Open Variation Database

L1CAM

0 unique

http://iudd.org/lovd/

LOVD 3.0-13

0 genes

0 variants

LOVD - Leiden Open Variation Database

0 unique

https://slc12a3.lovd.crscd.com/

LOVD 3.0-19

0 genes

0 variants

SLC12A3 LOVD

0 unique

https://slc5a2.lovd.crscd.com/

LOVD 3.0-19

0 genes

0 variants

SLC5A2 LOVD

0 unique

http://bipmed.iqm.unicamp.br/sclerosis/

LOVD 3.0-19

0 genes

0 variants

BIPMed

0 unique

http://clinbiodb2015.univ-angers.fr/LOVDv.3.0/

LOVD 3.0-13

0 genes

0 variants

#clinbiodb2015

0 unique

https://grenada.lumc.nl/LOVD2/shared1/

LOVD 2.0-36

0 genes

0 variants

LOVD - Leiden Open Variation Database

0 unique

http://bipmed.iqm.unicamp.br/LOVD/

LOVD 3.0-19

0 genes

0 variants

BRCA Challenge - BRAZIL

0 unique

https://grenada.lumc.nl/LOVD2/CDG/

LOVD 2.0-36

0 genes

0 variants

Congenital disorders of glycosylation (CDG)

0 unique

http://chromium.lovd.nl/LOVD2/

LOVD 2.0-36

0 genes

0 variants

LOVD - Leiden Open Variation Database

0 unique

https://cci.org

LOVD 3.0-19

? genes

? variants

LOVD - Leiden Open Variation Database

? unique

http://brca.iarc.fr/LOVD/

LOVD 2.0-22

? genes

? variants

LOVD - IARC

? unique

(This list is updated daily and shows LOVD 2.0 and 3.0 installations active for the last three months that have the "include in the global LOVD listing" setting enabled. Please allow one day for changes to take effect. Also, known 1.1.0 installations have been added.)

Last modified 2017/07/24 14:23:43 CEST

When using or discussing LOVD please refer to:
Fokkema IF, Taschner PE, Schaafsma GC, Celli J, Laros JF, den Dunnen JT (2011). LOVD v.2.0: the next generation in gene variant databases. Hum Mutat. 2011 May;32(5):557-63.

LOVD v.3.0 - Leiden Open Variation Database

Online gene-centered collection and display of DNA variations