Stop! Please note that LOVD2 is no longer supported. The last security release is from October 2020. Upgrade to LOVD3 to continue receiving updates.

The LOVD system in short:
LOVD stands for Leiden Open (source) Variation Database.
LOVD's purpose : To provide a flexible, freely available tool for Gene-centered collection and display of DNA variants.

LOVD features integration with the Mutalyzer sequence variant nomenclature checker, allowing for direct nomenclature checking of sequence variants during the submission process.

Information Are you interested in taking an LOVD course? Please send us a message and we'll keep you informed about the next LOVD course.

Question If you are looking for a specific gene database, please check the list of gene variant databases at the HGVS site, in our list of LSDBs, or in the list of registered LOVD installations.

LOVD's Popularity:

(Also see our public list of LOVD installations)
The number of IP adresses running an active LOVD (version 1.1.0-08 and up) installation, as measured until May, 2012. The total number of LOVD installations may be higher, since different installations at one server use one IP address.
LOVD usage for May, 2012

LOVD's statistics:

The total and unique number of variants contained in the single largest known LOVD install, as measured until May, 2012.
LMDp contents for May, 2012

Last modified 2019/02/21 15:22:59 CET

When using or discussing LOVD please refer to:
Fokkema IF, Taschner PE, Schaafsma GC, Celli J, Laros JF, den Dunnen JT (2011). LOVD v.2.0: the next generation in gene variant databases. Hum Mutat. 2011 May;32(5):557-63.

LOVD has received funding from the European Community's Seventh Framework Programme
(FP7/2007-2013) under grant agreement nº 200754 - the GEN2PHEN project.
Leiden University Medical Center, Netherlands
Ing. Ivo F.A.C. Fokkema, Dr. Johan T. den Dunnen