Variant and patient data

LOVD stores the variant and patient data separately. Each gene has it's own list of variants. Therefore, you first need to select a gene before you can view any variant and patient information. So if you enter a LOVD database website, you first need to select a gene to look at. If this LOVD installation contains only one gene, you are forwarded automatically. Selecting a gene forwards you to the gene's homepage.

At any time, you can switch to a different gene by clicking on the green icon on top of every page:
Switch gene database
Clicking the icon will show a drop-down list allowing you to select an other gene database. You will be forwarded to a similar page in the other database. For example: when viewing all disease-causing substitutions in one gene, using this way to switch genes will show you all disease-causing substitutions in the gene you selected.

The gene homepage will show you some general information on the gene, including the number of variants and patients stored in the database and external links with more information about this gene. All these links can be configured by the gene's curator.

If there are any variants stored in the gene's variant tables, additional links will be shown on the gene homepage; the unique variant listing, the complete variant listing, and the variants with no known pathogenicity. The first two are also available through the Variants tab.

« News feed Viewing and searching variant and patient data »

Last modified 2014/08/25 14:48:32 CEST

When using or discussing LOVD please refer to:
Fokkema IF, Taschner PE, Schaafsma GC, Celli J, Laros JF, den Dunnen JT (2011). LOVD v.2.0: the next generation in gene variant databases. Hum Mutat. 2011 May;32(5):557-63.

LOVD has received funding from the European Community's Seventh Framework Programme
(FP7/2007-2013) under grant agreement nº 200754 - the GEN2PHEN project.
Leiden University Medical Center, Netherlands
Ing. Ivo F.A.C. Fokkema, Dr. Johan T. den Dunnen