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Information For all details about LOVD, see our LOVD flyer! (last updated February 24th, 2010)

List of public LOVD installations

Question If you are looking for a specific gene database, please also check the list of gene variant databases at the HGVS site.

Please note that the latest available build is always installed on our Leiden server. We offer free use of this LOVD installation for those interested, e.g. to maintain/start a LSDB. Contact us for more information.

Show only LOVDs with gene symbol:

You can also download this list to see the complete list of genes in the databases.

In total: 387,899 variants (64,693 unique) in 105,337 patients in 24412 genes in 77 LOVD installations.
http://mitolsdb.igib.res.in/ LOVD 2.0-31 37 genes 142495 variants
mitolsdb MTATP6,MTATP8,MTCO1,MTCO2,MTCO3,MTCYB... 5170 unique
http://www.dmd.nl/nmdb2/ LOVD 2.0-33 92 genes 68285 variants
Leiden Muscular Dystrophy pages ACTA1,ACTC1,AGRN,ANO5,BAG3,BIN1,CAPN3... 9343 unique
http://chromium.liacs.nl/LOVD2/colon_cancer/ LOVD 2.0-33 10 genes 27164 variants
Colon cancer gene variant databases APC,CDH1,EPCAM,MLH1,MLH3,MSH2,MSH6,MU... 4411 unique
http://grenada.lumc.nl/LOVD2/MR/ LOVD 2.0-33 522 genes 26851 variants
X-chromosome gene database ABCB7,ABCD1,ACE2,ACOT9,ACSL4,ACTRT1,A... 3100 unique
https://grenada.lumc.nl/LOVD2/Usher_montpellier/ LOVD 2.0-33 10 genes 17113 variants
Retinal and hearing impairment genetic mutation database CDH23,CHM,CLRN1,GPR98,MYO7A,PCDH15,US... 2176 unique
http://grenada.lumc.nl/LOVD2/mendelian_genes/ LOVD 2.0-33 2033 genes 11411 variants
Mendelian genes A2M,A4GALT,AAAS,AANAT,AASS,ABAT,ABCA1... 3935 unique
http://www.genomed.org/LOVD/CM/ LOVD 2.0-30 56 genes 9716 variants
ZJU-CGGM & BGI-Shenzhen ABCC9,ACTC1,ACTN2,AXIN2,BARD1,BRIP1,C... 5925 unique
http://ccg.murdoch.edu.au/thalind/ LOVD 2.0-28 1 gene 9545 variants
ThalInd - A Database of beta thalassemia and hemoglobinopathies in India HBB 61 unique
http://chromium.liacs.nl/LOVD2/ LOVD 2.0-33 37 genes 8813 variants
LOVD - Leiden Open Variation Database ABCA13,ARG1,ASL,ASS1,ATM,ATP1A2,B3GAL... 3224 unique
http://grenada.lumc.nl/LOVD2/diabetes/ LOVD 2.0-33 3 genes 8083 variants
Monogenic Diabetes GCK,HNF1A,HNF4A 309 unique
http://grenada.lumc.nl/LOVD2/eye/ LOVD 2.0-33 58 genes 5035 variants
LOVD - Leiden Open Variation Database ABCA4,ADAMTS10,ADAMTSL4,ARL6,BFSP1,BF... 678 unique
https://research.cchmc.org/LOVD/ LOVD 2.0-33 47 genes 4556 variants
**PUBLIC** CCHMC Molecular Genetics Laboratory Mutation Database ABCB11,ABCB4,ACADM,ACADVL,ATP8B1,CASP... 4281 unique
http://chromium.liacs.nl/LOVD2/TSC/ LOVD 2.0-33 2 genes 4510 variants
Tuberous sclerosis database TSC1,TSC2 1817 unique
http://genomed.org/LOVD/LQTs/ LOVD 2.0-12 12 genes 2985 variants
Zhejiang University Center for Genetic and Genomic Medicine (ZJU-CGGM) AKAP9,ANK2,CACNA1C,CAV3,KCNE1,KCNE2,K... 1741 unique
http://rb1-lovd.d-lohmann.de/ LOVD 2.0-31 1 gene 2647 variants
rb1-lsdb RB1 1166 unique
http://chromium.liacs.nl/LOVD2/cancer/ LOVD 2.0-33 2 genes 2621 variants
LOVD - Leiden Open Variation Database BRCA1,BRCA2 1022 unique
https://grenada.lumc.nl/LOVD2/shared1/ LOVD 2.0-33 89 genes 2411 variants
LOVD - Leiden Open Variation Database AARS,ACP5,ALG11,ANKH,ARID1A,ASXL1,ATP... 781 unique
http://chromium.liacs.nl/LOVD2/FANC/ LOVD 2.0-33 15 genes 2275 variants
Fanconi anemia database BRIP1,FANCA,FANCB,FANCC,FANCD1,FANCD2... 785 unique
https://oi.gene.le.ac.uk/ LOVD 2.0-33 11 genes 2223 variants
Osteogenesis Imperfecta Variant Database BMP1,COL1A1,COL1A2,CRTAP,FKBP10,LEPRE... 1295 unique
http://grenada.lumc.nl/LOVD2/PKD/ LOVD 2.0-33 2 genes 2082 variants
Autosomal Dominant Polycystic Kidney Disease (ADPKD) PKD1,PKD2 70 unique
http://grenada.lumc.nl/LOVD2/COL4A/ LOVD 2.0-33 4 genes 2017 variants
Collagen, type IV, alpha COL4A3,COL4A4,COL4A5,COL4A6 1089 unique
http://lovd.bx.psu.edu/ LOVD 2.0-33 37 genes 1994 variants
The Globin Gene Server ALOX5AP,AQP9,ARG2,ASS1,ATRX,BCL11A,CN... 1938 unique
http://grenada.lumc.nl/LOVD2/vumc/ LOVD 2.0-33 7 genes 1819 variants
LOVD - Leiden Open Variation Database ALDH5A1,ASPA,D2HGDH,GAMT,GATM,L2HGDH,... 346 unique
http://www.genomed.org/lovd/mma/ LOVD 2.0-12 9 genes 1782 variants
Zhejiang University Center for Genetic and Genomic Medicine (ZJU-CGGM) LMBRD1,MCEE,MMAA,MMAB,MMACHC,MMADHC,M... 957 unique
http://grenada.lumc.nl/LOVD2/CDLS/ LOVD 2.0-33 5 genes 1431 variants
LOVD - Leiden Open Variation Database NIPBL,PDS5A,PDS5B,SMC1A,SMC3 308 unique
https://grenada.lumc.nl/LOVD2/CRD/ LOVD 2.0-33 130 genes 1217 variants
Childhood Recessive Diseases ACADL,ACADM,ACADSB,ACADVL,ADA,ADAMTS1... 303 unique
http://grenada.lumc.nl/LOVD2/VWF/ LOVD 2.0-33 1 gene 1175 variants
ISTH-SSC VWF Online Database VWF 421 unique
http://grenada.lumc.nl/LOVD2/ARVC/ LOVD 2.0-33 8 genes 1129 variants
ARVD/C Genetic Variants Database DSC2,DSG2,DSP,JUP,PKP2,TGFB3,TMEM43,TP63 599 unique
http://medgen.ugent.be/LOVD2/ LOVD 2.0-09 6 genes 1107 variants
LOVD - Center for Medical Genetics, Ghent, Belgium COL2A1,FOXL2,NF1_germline,NF1_somatic... 683 unique
http://medgen.ua.ac.be/LOVDv.2.0/ LOVD 2.0-33 2 genes 1091 variants
Multiple Osteochondroma Mutation Database EXT1,EXT2 651 unique
http://www.ncbi.nlm.nih.gov/lovd/ LOVD 2.0-33 5 genes 1029 variants
LOVD at NCBI ABCC6,DOCK8,FAS,IL2RG,OCRL 778 unique
https://lovd.euro-wabb.org/ LOVD 2.0-30 4 genes 1017 variants
EURO-WABB PROJECT OPEN VARIATION DATABASE ALMS1,EIF2AK3,SLC19A2,WFS1 358 unique
http://chromium.liacs.nl/LOVD2/SDH/ LOVD 2.0-33 6 genes 1010 variants
TCA Cycle Gene Mutation Database FH,SDHA,SDHAF2,SDHB,SDHC,SDHD 563 unique
http://www.dbpex.org/ LOVD 2.0-29 13 genes 985 variants
dbPEX, PEX Gene Database PEX1,PEX10,PEX12,PEX13,PEX14,PEX16,PE... 331 unique
http://genomed.org/LOVD/HNPCC/ LOVD 2.0-12 7 genes 639 variants
Zhejiang University Center for Genetic and Genomic Medicine (ZJU-CGGM) APC,MLH1,MLH3,MSH2,MSH6,PMS1,PMS2 450 unique
https://eds.gene.le.ac.uk/ LOVD 2.0-33 5 genes 583 variants
Ehlers-Danlos Syndrome Variant Database COL3A1,COL5A1,COL5A2,PLOD1,PLOD3 419 unique
http://hgddatabase.cvtisr.sk/ LOVD 2.0-31 1 gene 581 variants
HGD mutation database HGD 149 unique
https://chromium.liacs.nl/LOVD2/MG/ LOVD 2.0-33 1 gene 572 variants
LOVD - Leiden Open Variation Database MG 1 unique
http://ihg.helmholtz-muenchen.de/LOVDv.2.0/ LOVD 2.0-28 10 genes 564 variants
LOVD - Munich Open Variation Database ABCC8,DMP1,ENPP1,FGF23,KCNJ11,MC2R,MR... 204 unique
http://chromium.liacs.nl/LOVD2/growth/ LOVD 2.0-33 6 genes 491 variants
LOVD - Leiden Open Variation Database GHR,IGF1,IGF1R,IGF2,IGFALS,STAT5B 150 unique
http://grenada.lumc.nl/LOVD2/FHM/ LOVD 2.0-33 3 genes 456 variants
Familial Hemiplegic Migraine (FHM) Variation Database ATP1A2,CACNA1A,SCN1A 132 unique
https://grenada.lumc.nl/LOVD2/MD/ LOVD 2.0-33 1 gene 439 variants
Menkes Disease ATP7A 289 unique
http://www-huge.uni-regensburg.de/BEST1_database/ LOVD 2.0-23 1 gene 395 variants
Bestrophin 1 (BEST1) BEST1 271 unique
http://mitodyn.org/ LOVD 2.0-31 2 genes 384 variants
MITOchondrial DYNamics variation pages GDAP1,OPA1 58 unique
http://grenada.lumc.nl/LOVD2/TPI/ LOVD 2.0-33 6 genes 372 variants
Parkinson's disease Mutation Database LRRK2,PARK11,PARK2,PARK7,PINK1,SNCA 253 unique
http://ngrl.manchester.ac.uk/LOVDv.2.0/ LOVD 2.0-28 3 genes 372 variants
NGRL, Manchester LOVD CHM,L1CAM,UBE3A 310 unique
http://www.dbagenes.unito.it/ LOVD 2.0-25 9 genes 360 variants
Diamond-Blackfan Anemia RPL11,RPL35A,RPL5,RPS10,RPS17,RPS19,R... 223 unique
https://grenada.lumc.nl/LOVD2/ARC/ LOVD 2.0-33 2 genes 333 variants
LOVD - Leiden Open Variation Database VIPAR,VPS33B 251 unique
http://grenada.lumc.nl/LOVD2/ROR/ LOVD 2.0-33 2 genes 291 variants
LOVD 2.0 - ROR genes ROR1,ROR2 55 unique
http://grenada.lumc.nl/LOVD2/WS/ LOVD 2.0-33 5 genes 277 variants
LOVD - Leiden Open Variation Database EDN3,EDNRB,MITF,PAX3,SOX10 231 unique
http://sysbio.org.cn LOVD 2.0-33 16 genes 191 variants
Amyotrophic Lateral Sclerosis_NDDMD ANG,APEX1,APOE,CHMP2B,DCTN1,FUS,GRIA2... 87 unique
https://grenada.lumc.nl/LOVD2/PAX2/ LOVD 2.0-33 1 gene 181 variants
PAX2 variant database PAX2 58 unique
http://grenada.lumc.nl/LOVD2/ctx/ LOVD 2.0-33 1 gene 172 variants
Cerebrotendinous Xanthomatosis CYP27A1 57 unique
http://149.142.212.78/LOVD/ LOVD 2.0-31 1 gene 158 variants
UCLA Neurogenetics SETX Database SETX 97 unique
http://www.skingenedatabase.com/ LOVD 2.0-16 1 gene 150 variants
The Folliculin Mutation Database FLCN 84 unique
http://grenada.lumc.nl/LOVD2/amc/ LOVD 2.0-33 1 gene 107 variants
LOVD - Leiden Open Variation Database PORCN 81 unique
http://www.goldenhelix.org/server/a1atvar/ LOVD 2.0-30 1 gene 93 variants
a1atvar SERPINA1 65 unique
http://sysbio.org.cn/ LOVD 2.0-33 3 genes 55 variants
Alzheimer's disease_NDDMD APP,PSEN1,PSEN2 55 unique
https://grenada.lumc.nl/LOVD2/TCS/ LOVD 2.0-33 2 genes 26 variants
Treacher Collins syndrome variant database POLR1C,POLR1D 22 unique
https://grenada.lumc.nl/LOVD2/BCM/ LOVD 2.0-33 1 gene 24 variants
Baylor College of Medicine KAT6B 19 unique
https://grenada.lumc.nl/LOVD3/shared/ LOVD 3.0-beta-01 21019 genes 4 variants
LOVD 3.0 test installation A1BG,A1BG-AS1,A1CF,A2LD1,A2M,A2ML1,A4... 4 unique
http://www.medgen.mcgill.ca/nndi/ LOVD 2.0-16 1 gene 2 variants
nndi AVP 1 unique
http://www.med.uni-magdeburg.de/lovd/ LOVD 2.0-26 1 gene 2 variants
Magdeburg Mutation Database LAMB2 1 unique
http://www.medgen.mcgill.ca/ANO5/ LOVD 2.0-24 1 gene 1 variants
ANO5 LOVD - Leiden Open Variation Database ANO5 1 unique
https://grenada.lumc.nl/LOVD2/vumc/CTD/ LOVD 2.0-33 5 genes 0 variants
Connective tissue disorders (VUMC Amsterdam) ACTA2,ADAMTS2,COL10A1,COL4A1,MYH11 0 unique
https://grenada.lumc.nl/LOVD2/CILD/ LOVD 2.0-33 5 genes 0 variants
Primary Ciliary Dyskinesia variant database DNAAF1,DNAH11,DNAH5,DNAI1,DNAI2 0 unique
https://grenada.lumc.nl/LOVD2/uni-hd/5-HT/ LOVD 2.0-33 5 genes 0 variants
University of Heidelberg Serotonin variant database HTR3A,HTR3B,HTR3C,HTR3D,HTR3E 0 unique
https://grenada.lumc.nl/LOVD2/UCL-Heart/ LOVD 2.0-33 3 genes 0 variants
HEART UCL LDLR,LDLRAP1,PCSK9 0 unique
https://atlas.cmm.ki.se/LOVDv.2.0/ LOVD 2.0-31 1 gene 0 variants
LOVD - Leiden Open Variation Database MLH1 0 unique
https://grenada.lumc.nl/LOVD2/uni-hd/TF/ LOVD 2.0-33 1 gene 0 variants
University of Heidelberg Transcription factor variant database SHOX 0 unique
http://grenada.lumc.nl/LOVD2/L1CAM/ LOVD 2.0-33 1 gene 0 variants
LOVD - Leiden Open Variation Database L1CAM 0 unique
http://172.30.12.152/DB/LOVD3 LOVD 3.0-alpha-07 0 genes 0 variants
MUMC - Maastricht Open Variation Database 0 unique
http://HCI-LOVD.hci.utah.edu LOVD 2.0-33 0 genes 0 variants
LOVD - human mismatch repair genes 0 unique
https://grenada.lumc.nl/LOVD2/NIH/eyegene/ LOVD 2.0-33 0 genes 0 variants
LOVD - Leiden Open Variation Database 0 unique
http://dnadb.info/ LOVD 2.0-31 0 genes 0 variants
International DNA Database 0 unique
https://grenada.lumc.nl/LOVD2/CDG/ LOVD 2.0-33 0 genes 0 variants
Congenital disorders of glycosylation (CDG) 0 unique
http://lovd.hgu.mrc.ac.uk/ LOVD 2.0-30 ? genes ? variants
Human Genetics Unit LOVD ? unique
(This list is updated daily and shows LOVD 2.0 installations active for the last three months that have the "include in the global LOVD listing" setting enabled. Please allow one day for changes to take effect. Also, known 1.1.0 installations have been added.)

Last modified 2012/01/25 17:03:13 CET

When using or discussing LOVD please refer to:
Fokkema IF, Taschner PE, Schaafsma GC, Celli J, Laros JF, den Dunnen JT (2011). LOVD v.2.0: the next generation in gene variant databases. Hum Mutat. 2011 May;32(5):557-63.

LOVD has received funding from the European Community's Seventh Framework Programme
(FP7/2007-2013) under grant agreement nº 200754 - the GEN2PHEN project.
Leiden University Medical Center, Netherlands
Ing. Ivo F.A.C. Fokkema, Dr. Johan T. den Dunnen