Information For all details about LOVD, see our LOVD flyer! (last updated June 6th, 2013)
By the way, did you already know LOVD 3.0 is out?

List of public LOVD installations

Question If you are looking for a specific gene database, please also check our list of LSDBs.

Please note that the latest available build is always installed on our Leiden server. We offer free use of this LOVD installation for those interested, e.g. to maintain/start a LSDB. Contact us for more information.

Show only LOVDs with gene symbol:

You can also download this list to see the complete list of genes in the databases.

In total: 3,913,734 variants (2,943,439 unique) in 425,101 individuals in 85 LOVD installations.
http://databases.lovd.nl/whole_genome/ LOVD 3.0-20a 22002 genes 1998175 variants
Whole genome datasets A1BG,A1BG-AS1,A1CF,A2M,A2M-AS1,A2ML1,... 1998135 unique
http://bipmed.iqm.unicamp.br/ LOVD 3.0-17 20930 genes 624137 variants
BIPMed WES A1BG,A1BG-AS1,A1CF,A2M,A2M-AS1,A2ML1,... 622610 unique
https://databases.lovd.nl/shared/ LOVD 3.0-20b 22977 genes 527989 variants
Shared database A1BG,A1BG-AS1,A1CF,A2LD1,A2M,A2M-AS1,... 74676 unique
http://proteomics.bio21.unimelb.edu.au/lovd/ LOVD 3.0-07 14772 genes 239690 variants
LOVD - Leiden Open Variation Database A1BG,A1BG-AS1,A1CF,A2M,A2ML1,A4GALT,A... 152241 unique
http://bipmed.iqm.unicamp.br/cfa/ LOVD 3.0-20 41 genes 134333 variants
Craniofacial anomalies APOC2,APOC4-APOC2,AXIN2,BCL3,BMP4,CLP... 257 unique
https://ab-openlab.csir.res.in/mitolsdb/ LOVD 2.0-35 37 genes 112662 variants
MitoLSDB MTATP6,MTATP8,MTCO1,MTCO2,MTCO3,MTCYB... 4660 unique
http://www.dmd.nl/nmdb2/ LOVD 2.0-36 95 genes 42929 variants
Leiden Muscular Dystrophy pages ANKRD1,B3GNT1,BAG3,BANF1,BIN1,CAPN3,C... 7770 unique
http://grenada.lumc.nl/LOVD2/mendelian_genes/ LOVD 2.0-36 200 genes 26738 variants
Mendelian genes ABO,ACTB,ACTG1,ACVR1,ADA,ADAMTS13,ADA... 5105 unique
http://HCI-LOVD.hci.utah.edu LOVD 2.0-33 8 genes 26167 variants
LOVD - human mismatch repair genes MLH1,MLH1_priors,MSH2,MSH2_priors,MSH... 26167 unique
http://chromium.lovd.nl/LOVD2/colon_cancer/ LOVD 2.0-36 9 genes 25621 variants
Colon cancer gene variant databases APC,CDH1,GALNT12,MLH1,MLH3,MSH2,MSH6,... 3434 unique
https://grenada.lumc.nl/LOVD2/Usher_montpellier/ LOVD 2.0-36 20 genes 23483 variants
Retinal and hearing impairment genetic mutation database CDH23,CEACAM16,CERKL,CHM,CLDN14,CLRN1... 3646 unique
http://grenada.lumc.nl/LOVD2/MR/ LOVD 2.0-36 427 genes 20579 variants
X-chromosome gene database ACOT9,ACSL4,ACTRT1,AFF2,AGTR2,AKAP14,... 1431 unique
http://chromium.lovd.nl/LOVD2/TSC/ LOVD 2.0-36 2 genes 19361 variants
Tuberous sclerosis database TSC1,TSC2 3780 unique
http://www.insight-database.org/ LOVD 3.0-19 14 genes 16561 variants
International Society for Gastrointestinal Hereditary Tumours Database APC,EPCAM,FBXO11,MLH1,MLH3,MSH2,MSH3,... 3449 unique
http://www.genomed.org/lovd2/ LOVD 2.0-35 96 genes 15133 variants
Zhejiang University Center for Genetic and Genomic Medicine (ZJU-CGGM) ABCC9,ACTC1,ACTN2,AKAP9,ANK2,APC,AXIN... 9327 unique
http://grenada.lumc.nl/LOVD2/diabetes/ LOVD 2.0-36 3 genes 9783 variants
Monogenic Diabetes GCK,HNF1A,HNF4A 690 unique
http://bioinf.suda.edu.cn/NDDvarbase/LOVDv.3.0/ LOVD 3.0-20a 226 genes 5946 variants
NDDVD - Neurodegenerative Diseases Variation Database ABCA7,ADCY5,ADORA1,AFG3L2,AGBL3,ALS2,... 4678 unique
https://oi.gene.le.ac.uk/ LOVD 2.0-36 19 genes 3733 variants
Osteogenesis Imperfecta Variant Database BMP1,COL1A1,COL1A2,CREB3L1,CRTAP,FKBP... 1891 unique
https://lovd.euro-wabb.org/ LOVD 2.0-36 23 genes 3566 variants
EURO-WABB PROJECT OPEN VARIATION DATABASE ALMS1,ARL6,BBIP1,BBS1,BBS10,BBS12,BBS... 1124 unique
http://databases.lovd.nl/DNA_profiles/ LOVD 3.0-20a 0 genes 3414 variants
LOVD - Leiden Open Variation Database 667 unique
http://rb1-lovd.d-lohmann.de/ LOVD 2.0-34 1 gene 3390 variants
rb1-lsdb RB1 1748 unique
http://grenada.lumc.nl/LOVD2/vumc/ LOVD 2.0-36 7 genes 2980 variants
LOVD - Leiden Open Variation Database ALDH5A1,ASPA,D2HGDH,GAMT,GATM,L2HGDH,... 617 unique
http://lovd.bx.psu.edu/ LOVD 2.0-36 37 genes 2260 variants
The Globin Gene Server ALOX5AP,AQP9,ARG2,ASS1,ATRX,BCL11A,CN... 2202 unique
http://grenada.lumc.nl/LOVD2/VWF/ LOVD 2.0-36 2 genes 2151 variants
EAHAD Coagulation Factor Variant Databases GP1BA,VWF 739 unique
http://lsdb.hgu.mrc.ac.uk/ LOVD 2.0-30 11 genes 1862 variants
MRC Human Genetics Unit LOVD at MRC IGMM MLYCD,NIPBL,OTX2,PAX6,RAB18,RAB3GAP1,... 1092 unique
https://eds.gene.le.ac.uk/ LOVD 2.0-36 12 genes 1638 variants
Ehlers Danlos Syndrome Variant Database ADAMTS2,B3GALT6,B4GALT7,CHST14,COL3A1... 1009 unique
http://grenada.lumc.nl/LOVD2/ARVC/ LOVD 2.0-36 8 genes 1555 variants
ARVD/C Genetic Variants Database DSC2,DSG2,DSP,JUP,PKP2,TGFB3,TMEM43,TP63 1027 unique
http://grenada.lumc.nl/LOVD2/CDLS/ LOVD 2.0-36 5 genes 1512 variants
LOVD - Leiden Open Variation Database NIPBL,PDS5A,PDS5B,SMC1A,SMC3 366 unique
http://secure.ngrl.org.uk/LOVDv.2.0/ LOVD 2.0-28 5 genes 1404 variants
NGRL, Manchester LOVD CHM,KDM6A,L1CAM,MLL2,UBE3A 540 unique
http://databases.lovd.ni/shared/ LOVD 3.0-14 11 genes 1312 variants
LOVD - Leiden Open Variation Database APC,CCND1,CXCL8,KRAS,MLH1,MSH2,MSH6,N... 55 unique
http://grenada.lumc.nl/LOVD2/TPI/ LOVD 2.0-36 9 genes 1127 variants
Parkinson's disease Mutation Database ATXN2,DNAJC13,GBA,LRRK2,PARK2,PARK7,P... 983 unique
http://medgen.ua.ac.be/LOVDv.2.0/ LOVD 2.0-33 2 genes 1110 variants
Multiple Osteochondroma Mutation Database EXT1,EXT2 663 unique
http://www.dbpex.org/ LOVD 2.0-30 13 genes 1081 variants
dbPEX, PEX Gene Database PEX1,PEX10,PEX12,PEX13,PEX14,PEX16,PE... 389 unique
http://mseqdr.lumc.edu/GEDI/ LOVD 3.0-08 298 genes 1012 variants
The Genetic Eye Disorder (GEDI) Variation Database ABCA4,ABCC6,ABHD12,ADAM9,ADAMTS18,AFG... 981 unique
http://hgddatabase.cvtisr.sk/ LOVD 2.0-36 1 gene 826 variants
HGD mutation database HGD 203 unique
http://mitodyn.org/ LOVD 2.0-36 2 genes 813 variants
MITOchondrial DYNamics variation pages GDAP1,OPA1 418 unique
http://143.169.238.105/LOVD/ LOVD 3.0-16 6 genes 688 variants
Loeys-Dietz Syndrome Mutation Database SMAD2,SMAD3,TGFB2,TGFB3,TGFBR1,TGFBR2 306 unique
http://hci-exlovd.hci.utah.edu/ LOVD 2.0-22 3 genes 659 variants
Database of BRCA1 and BRCA2 sequence variants that have been clinically reclassified using a quantit BRCA1,BRCA1fx,BRCA2 512 unique
https://coppolalab.ucla.edu/lovd_gift/ LOVD 3.0-19 11 genes 631 variants
Coppola Lab - GIFT Variant Database APP,C9orf72,CHMP2B,FUS,GRN,MAPT,PSEN1... 582 unique
https://grenada.lumc.nl/LOVD2/MD/ LOVD 2.0-36 1 gene 510 variants
Menkes Disease ATP7A 323 unique
http://grenada.lumc.nl/LOVD2/FHM/ LOVD 2.0-36 3 genes 500 variants
Familial Hemiplegic Migraine (FHM) Variation Database ATP1A2,CACNA1A,SCN1A 143 unique
http://www.dbagenes.unito.it/ LOVD 2.0-36 13 genes 398 variants
Diamond-Blackfan Anemia GATA1,RPL11,RPL15,RPL26,RPL31,RPL35A,... 255 unique
http://www-huge.uni-regensburg.de/BEST1_database/ LOVD 2.0-23 1 gene 394 variants
Bestrophin 1 (BEST1) BEST1 269 unique
http://grenada.lumc.nl/LOVD2/WS/ LOVD 2.0-36 5 genes 368 variants
LOVD - Leiden Open Variation Database EDN3,EDNRB,MITF,PAX3,SOX10 291 unique
https://grenada.lumc.nl/LOVD2/ARC/ LOVD 2.0-36 2 genes 333 variants
LOVD - Leiden Open Variation Database VIPAR,VPS33B 251 unique
http://dna2.leeds.ac.uk/LOVD/ LOVD 3.0-13 18 genes 307 variants
LOVD - Leiden Open Variation Database ACPT,AMBN,AMELX,AMTN,C4orf26,COL17A1,... 198 unique
http://grenada.lumc.nl/LOVD2/ROR/ LOVD 2.0-36 2 genes 291 variants
LOVD 2.0 - ROR genes ROR1,ROR2 55 unique
http://www.icp.ucl.ac.be/vikkula/VAdb/ LOVD 2.0-36 16 genes 248 variants
Vascular Anomaly and Lymphedema Mutation Database CCBE1,CCM2,FLT4,FOXC2,GATA2,GJC2,GLMN... 168 unique
https://grenada.lumc.nl/LOVD2/PAX2/ LOVD 2.0-36 1 gene 248 variants
PAX2 variant database PAX2 83 unique
http://ec2-52-59-113-2.eu-central-1.compute.amazonaws.com/LOVD/ LOVD 3.0-16 2 genes 216 variants
LOVD - Leiden Open Variation Database PKD1,PKD2 1 unique
http://grenada.lumc.nl/LOVD2/ctx/ LOVD 2.0-36 1 gene 213 variants
Cerebrotendinous Xanthomatosis CYP27A1 69 unique
https://lovd3.isciii.es/ LOVD 3.0-11 31 genes 188 variants
SpainMDB ABCD1,APC,ATP7B,BRAF,BRCA1,BRCA2,BSND... 137 unique
https://grenada.lumc.nl/LOVD2/NIH/eyegene/ LOVD 2.0-36 4 genes 186 variants
LOVD - Leiden Open Variation Database CHM,PRPF8,RB1,RHO 73 unique
https://drdb.gene.le.ac.uk/ LOVD 2.0-36 4 genes 184 variants
Death Receptor Database (DRdb) TNFRSF10A,TNFRSF10B,TNFRSF10C,TNFRSF10D 144 unique
http://grenada.lumc.nl/LOVD2/amc/ LOVD 2.0-36 1 gene 171 variants
LOVD - Leiden Open Variation Database PORCN 119 unique
https://grenada.lumc.nl/LOVD2/uni-hd/5-HT/ LOVD 2.0-36 5 genes 170 variants
University of Heidelberg Serotonin receptor variant database HTR3A,HTR3B,HTR3C,HTR3D,HTR3E 73 unique
http://bipmed.iqm.unicamp.br/BRCA-challenge/ LOVD 3.0-20 2 genes 162 variants
BRCA Challenge - BRAZIL BRCA1,BRCA2 148 unique
http://nndimontreal.ca/lovd3/ LOVD 3.0-19 1 gene 115 variants
LOVD - Leiden Open Variation Database AVP 68 unique
http://server.goldenhelix.org/a1atvar/ LOVD 2.0-30 1 gene 94 variants
a1atvar SERPINA1 66 unique
http://db.cshg.org.cy/ LOVD 3.0-17 44 genes 86 variants
APC,APCS,ATP6V1B1,BRCA1,BRCA2,C1QA,C1... 83 unique
http://sysbio.org.cn LOVD 2.0-33 1 gene 80 variants
Alexander disease_NDDMD GFAP 70 unique
http://dna2.leeds.ac.uk/GRK1_LOVD/ LOVD 3.0-18 1 gene 59 variants
LOVD - Leiden Open Variation Database GRK1 23 unique
http://www.icp.ucl.ac.be/vikkula/CLPdb/ LOVD 2.0-36 1 gene 54 variants
Cleft Lip and Palate Mutation Database IRF6 44 unique
http://databases.locd.nl/shared/ LOVD 3.0-13 3 genes 43 variants
National Thalassemia Database HBA1,HBA2,HBB 24 unique
http://ibio-cn.org LOVD 2.0-31 1 gene 30 variants
Canavan Disease_NDDMD ASPA 22 unique
http://www.genetik-regensburg.de/LOVDv.3.0/ LOVD 3.0-16 37 genes 29 variants
Labor Staber Humangenetik AIP,ATM,ATP7B,ATXN3,BRCA1,BRCA2,CFTR,... 28 unique
https://grenada.lumc.nl/LOVD2/TCS/ LOVD 2.0-36 2 genes 26 variants
Treacher Collins syndrome variant database POLR1C,POLR1D 22 unique
http://bipmed.iqm.unicamp.br/epileptic-encephalopathy/ LOVD 3.0-19 1 gene 16 variants
BIPMed - Epileptic Encephalopathy SCN1A 16 unique
https://slc12a3.lovd.crscd.com/ LOVD 3.0-19 1 gene 3 variants
SLC12A3 LOVD SLC12A3 2 unique
http://www.medgen.mcgill.ca/ANO5/ LOVD 2.0-24 1 gene 1 variants
ANO5 LOVD - Leiden Open Variation Database ANO5 1 unique
http://genet.ir/variome/ LOVD 3.0-14 9063 genes 0 variants
Iran Variation Database A2M,A2ML1,A4GALT,AACS,AADACL2,AADAT,A... 0 unique
https://grenada.lumc.nl/LOVD2/CILD/ LOVD 2.0-36 5 genes 0 variants
Primary Ciliary Dyskinesia variant database DNAAF1,DNAH11,DNAH5,DNAI1,DNAI2 0 unique
http://bipmed.iqm.unicamp.br/tuberous-sclerosis/ LOVD 3.0-17 3 genes 0 variants
BIPMed - Variants in tuberous sclerosis patients from Brazil PKD1,TSC1,TSC2 0 unique
http://grenada.lumc.nl/LOVD2/L1CAM/ LOVD 2.0-36 1 gene 0 variants
LOVD - Leiden Open Variation Database L1CAM 0 unique
http://l3.d-lohmann.de/ LOVD 3.0-18 1 gene 0 variants
Essen-Eye-Cancer-Genetics RB1 0 unique
https://slc5a2.lovd.crscd.com/ LOVD 3.0-19 0 genes 0 variants
SLC5A2 LOVD 0 unique
http://bipmed.iqm.unicamp.br/LOVD/ LOVD 3.0-19 0 genes 0 variants
BRCA Challenge - BRAZIL 0 unique
http://chromium.lovd.nl/LOVD2/ LOVD 2.0-36 0 genes 0 variants
LOVD - Leiden Open Variation Database 0 unique
http://iudd.org/lovd/ LOVD 3.0-13 0 genes 0 variants
LOVD - Leiden Open Variation Database 0 unique
http://cwlovd.com LOVD 3.0-20a 0 genes 0 variants
LOVD - Leiden Open Variation Database 0 unique
http://clinbiodb2015.univ-angers.fr/LOVDv.3.0/ LOVD 3.0-13 0 genes 0 variants
#clinbiodb2015 0 unique
https://grenada.lumc.nl/LOVD2/CDG/ LOVD 2.0-36 0 genes 0 variants
Congenital disorders of glycosylation (CDG) 0 unique
https://grenada.lumc.nl/LOVD2/shared1/ LOVD 2.0-36 0 genes 0 variants
LOVD - Leiden Open Variation Database 0 unique
http://bipmed.iqm.unicamp.br/sclerosis/ LOVD 3.0-19 0 genes 0 variants
BIPMed 0 unique
http://brca.iarc.fr/LOVD/ LOVD 2.0-22 ? genes ? variants
LOVD - IARC ? unique
(This list is updated daily and shows LOVD 2.0 and 3.0 installations active for the last three months that have the "include in the global LOVD listing" setting enabled. Please allow one day for changes to take effect. Also, known 1.1.0 installations have been added.)

Last modified 2017/07/21 18:19:48 CEST

When using or discussing LOVD please refer to:
Fokkema IF, Taschner PE, Schaafsma GC, Celli J, Laros JF, den Dunnen JT (2011). LOVD v.2.0: the next generation in gene variant databases. Hum Mutat. 2011 May;32(5):557-63.

LOVD has received funding from the European Community's Seventh Framework Programme
(FP7/2007-2013) under grant agreement nº 200754 - the GEN2PHEN project.
Leiden University Medical Center, Netherlands
Ing. Ivo F.A.C. Fokkema, Dr. Johan T. den Dunnen