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Information For all details about LOVD, see our LOVD flyer! (last updated February 24th, 2010)
By the way, did you already know LOVD 3.0 is out?

List of public LOVD installations

Question If you are looking for a specific gene database, please also check the list of gene variant databases at the HGVS site.

Please note that the latest available build is always installed on our Leiden server. We offer free use of this LOVD installation for those interested, e.g. to maintain/start a LSDB. Contact us for more information.

Show only LOVDs with gene symbol:

You can also download this list to see the complete list of genes in the databases.

In total: 2,535,840 variants (2,126,882 unique) in 172,602 individuals in 47570 genes in 89 LOVD installations.
http://databases.lovd.nl/whole_genome/ LOVD 3.0-04 22002 genes 1998204 variants
Whole genome datasets A1BG,A1BG-AS1,A1CF,A2M,A2M-AS1,A2ML1,... 1990829 unique
http://mitolsdb.igib.res.in/ LOVD 2.0-31 37 genes 142495 variants
mitolsdb MTATP6,MTATP8,MTCO1,MTCO2,MTCO3,MTCYB... 5170 unique
http://www.dmd.nl/nmdb2/ LOVD 2.0-35 157 genes 80459 variants
Leiden Muscular Dystrophy pages ACTA1,ACTC1,AGRN,ANKRD1,ANO5,ARHGEF10... 13456 unique
http://grenada.lumc.nl/LOVD2/mendelian_genes/ LOVD 2.0-35 1873 genes 48772 variants
Mendelian genes A2M,A4GALT,AAAS,AANAT,AASS,ABAT,ABCA1... 7973 unique
http://grenada.lumc.nl/LOVD2/MR/ LOVD 2.0-35 519 genes 29055 variants
X-chromosome gene database ABCB7,ABCD1,ACE2,ACOT9,ACSL4,ACTRT1,A... 4306 unique
http://chromium.liacs.nl/LOVD2/colon_cancer/ LOVD 2.0-35 11 genes 27443 variants
Colon cancer gene variant databases APC,CDH1,EPCAM,GALNT12,MLH1,MLH3,MSH2... 4541 unique
http://databases.lovd.nl/shared/ LOVD 3.0-04 22033 genes 27007 variants
LOVD 3.0 shared installation A1BG,A1BG-AS1,A1CF,A2LD1,A2M,A2M-AS1,... 15786 unique
http://HCI-LOVD.hci.utah.edu LOVD 2.0-33 4 genes 26458 variants
LOVD - human mismatch repair genes MLH1,MSH2,MSH6,PMS2 25869 unique
https://grenada.lumc.nl/LOVD2/Usher_montpellier/ LOVD 2.0-35 15 genes 19304 variants
Retinal and hearing impairment genetic mutation database CDH23,CHM,CLRN1,GPR98,MYO15A,MYO7A,OT... 2536 unique
http://databases.lovd.nl/genomed/ LOVD 2.0-34 82 genes 15397 variants
Zhejiang University Center for Genetic and Genomic Medicine (ZJU-CGGM) ABCC9,ACTC1,ACTN2,AKAP9,ANK2,AXIN2,BA... 9230 unique
http://www.genomed.org/lovd2/ LOVD 2.0-35 91 genes 14663 variants
Zhejiang University Center for Genetic and Genomic Medicine (ZJU-CGGM) ABCC9,ACTC1,ACTN2,AKAP9,ANK2,APC,AXIN... 9149 unique
http://grenada.lumc.nl/LOVD2/diabetes/ LOVD 2.0-35 3 genes 9687 variants
Monogenic Diabetes GCK,HNF1A,HNF4A 695 unique
http://ccg.murdoch.edu.au/thalind/ LOVD 2.0-28 1 gene 9545 variants
ThalInd - A Database of beta thalassemia and hemoglobinopathies in India HBB 61 unique
http://chromium.liacs.nl/LOVD2/ LOVD 2.0-35 38 genes 9456 variants
LOVD - Leiden Open Variation Database ABCA13,ADAR,ARG1,ASL,ASS1,ATM,ATP1A2,... 3411 unique
http://chromium.liacs.nl/LOVD2/TSC/ LOVD 2.0-35 2 genes 9071 variants
Tuberous sclerosis database TSC1,TSC2 2294 unique
http://grenada.lumc.nl/LOVD2/eye/ LOVD 2.0-35 208 genes 9033 variants
Eye diseases - LOVD ABCA4,ABCB5,ABCC6,ABHD12,ACBD5,ADAM9,... 1743 unique
https://grenada.lumc.nl/LOVD2/shared1/ LOVD 2.0-35 133 genes 5867 variants
LOVD - Leiden Open Variation Database AARS,ACO2,ACP5,AGK,ALG11,ANKH,ARID1A,... 1468 unique
https://research.cchmc.org/LOVD2/ LOVD 2.0-34 47 genes 4561 variants
**PUBLIC** CCHMC Molecular Genetics Laboratory Mutation Database ABCB11,ABCB4,ACADM,ACADVL,ATP8B1,CASP... 4286 unique
http://rb1-lovd.d-lohmann.de/ LOVD 2.0-34 1 gene 3079 variants
rb1-lsdb RB1 1516 unique
http://www.genomed.org/LOVD/LQTs/ LOVD 2.0-12 12 genes 2985 variants
Zhejiang University Center for Genetic and Genomic Medicine (ZJU-CGGM) AKAP9,ANK2,CACNA1C,CAV3,KCNE1,KCNE2,K... 1741 unique
https://lovd.euro-wabb.org/ LOVD 2.0-30 22 genes 2779 variants
EURO-WABB PROJECT OPEN VARIATION DATABASE ALMS1,ARL6,BBS1,BBS10,BBS12,BBS2,BBS4... 837 unique
http://chromium.liacs.nl/LOVD2/cancer/ LOVD 2.0-35 2 genes 2649 variants
LOVD - Leiden Open Variation Database BRCA1,BRCA2 1037 unique
https://oi.gene.le.ac.uk/ LOVD 2.0-35 14 genes 2528 variants
Osteogenesis Imperfecta Variant Database BMP1,COL1A1,COL1A2,CRTAP,FKBP10,IFITM... 1407 unique
http://chromium.liacs.nl/LOVD2/FANC/ LOVD 2.0-35 15 genes 2475 variants
Fanconi anemia database FANCA,FANCB,FANCC,FANCD1,FANCD2,FANCE... 797 unique
http://grenada.lumc.nl/LOVD2/COL4A/ LOVD 2.0-35 4 genes 2281 variants
Collagen, type IV, alpha COL4A3,COL4A4,COL4A5,COL4A6 1191 unique
http://grenada.lumc.nl/LOVD2/PKD/ LOVD 2.0-35 2 genes 2156 variants
Autosomal Dominant Polycystic Kidney Disease (ADPKD) PKD1,PKD2 76 unique
http://lovd.bx.psu.edu/ LOVD 2.0-35 37 genes 2053 variants
The Globin Gene Server ALOX5AP,AQP9,ARG2,ASS1,ATRX,BCL11A,CN... 1996 unique
http://grenada.lumc.nl/LOVD2/VWF/ LOVD 2.0-35 4 genes 1965 variants
ISTH-SSC VWF Online Database F8,F9,GP1BA,VWF 632 unique
http://www.ucl.ac.uk/ldlr/Current/ LOVD 1.1.0-12 3 genes 1943 variants
British Heart Foundation LDLR,LDLRAP1,PCSK9 1255 unique
http://grenada.lumc.nl/LOVD2/vumc/ LOVD 2.0-35 7 genes 1867 variants
LOVD - Leiden Open Variation Database ALDH5A1,ASPA,D2HGDH,GAMT,GATM,L2HGDH,... 356 unique
http://lsdb.hgu.mrc.ac.uk/ LOVD 2.0-30 11 genes 1563 variants
MRC Human Genetics Unit LOVD at MRC IGMM MLYCD,NIPBL,OTX2,PAX6,RAB18,RAB3GAP1,... 933 unique
http://grenada.lumc.nl/LOVD2/CDLS/ LOVD 2.0-35 5 genes 1440 variants
LOVD - Leiden Open Variation Database NIPBL,PDS5A,PDS5B,SMC1A,SMC3 314 unique
http://grenada.lumc.nl/LOVD2/ARVC/ LOVD 2.0-35 8 genes 1129 variants
ARVD/C Genetic Variants Database DSC2,DSG2,DSP,JUP,PKP2,TGFB3,TMEM43,TP63 605 unique
http://medgen.ugent.be/LOVD2/ LOVD 2.0-09 6 genes 1118 variants
LOVD - Center for Medical Genetics, Ghent, Belgium COL2A1,FOXL2,NF1_germline,NF1_somatic... 694 unique
http://grenada.lumc.nl/LOVD2/TPI/ LOVD 2.0-35 6 genes 1115 variants
Parkinson's disease Mutation Database LRRK2,PARK11,PARK2,PARK7,PINK1,SNCA 981 unique
http://medgen.ua.ac.be/LOVDv.2.0/ LOVD 2.0-33 2 genes 1098 variants
Multiple Osteochondroma Mutation Database EXT1,EXT2 654 unique
http://www.dbpex.org/ LOVD 2.0-29 13 genes 1079 variants
dbPEX, PEX Gene Database PEX1,PEX10,PEX12,PEX13,PEX14,PEX16,PE... 388 unique
http://chromium.liacs.nl/LOVD2/SDH/ LOVD 2.0-35 6 genes 1051 variants
TCA Cycle Gene Mutation Database FH,SDHA,SDHAF2,SDHB,SDHC,SDHD 575 unique
http://www.ncbi.nlm.nih.gov/lovd/ LOVD 2.0-35 6 genes 1034 variants
LOVD at NCBI ABCC6,DOCK8,FAS,FOXA1,IL2RG,OCRL 781 unique
https://eds.gene.le.ac.uk/ LOVD 2.0-35 7 genes 756 variants
Ehlers-Danlos Syndrome Variant Database ADAMTS2,CHST14,COL3A1,COL5A1,COL5A2,P... 543 unique
http://hgddatabase.cvtisr.sk/ LOVD 2.0-31 1 gene 673 variants
HGD mutation database HGD 156 unique
http://mitodyn.org/ LOVD 2.0-35 2 genes 671 variants
MITOchondrial DYNamics variation pages GDAP1,OPA1 337 unique
http://genomed.org/LOVD/HNPCC/ LOVD 2.0-12 7 genes 639 variants
Zhejiang University Center for Genetic and Genomic Medicine (ZJU-CGGM) APC,MLH1,MLH3,MSH2,MSH6,PMS1,PMS2 450 unique
http://ihg.helmholtz-muenchen.de/LOVDv.2.0/ LOVD 2.0-28 10 genes 582 variants
LOVD - Munich Open Variation Database ABCC8,DMP1,ENPP1,FGF23,KCNJ11,MC2R,MR... 211 unique
https://chromium.liacs.nl/LOVD2/MG/ LOVD 2.0-35 1 gene 572 variants
LOVD - Leiden Open Variation Database MG 1 unique
https://grenada.lumc.nl/LOVD2/MD/ LOVD 2.0-35 1 gene 507 variants
Menkes Disease ATP7A 320 unique
http://grenada.lumc.nl/LOVD2/FHM/ LOVD 2.0-35 3 genes 500 variants
Familial Hemiplegic Migraine (FHM) Variation Database ATP1A2,CACNA1A,SCN1A 143 unique
http://chromium.liacs.nl/LOVD2/growth/ LOVD 2.0-35 6 genes 491 variants
LOVD - Leiden Open Variation Database GHR,IGF1,IGF1R,IGF2,IGFALS,STAT5B 150 unique
http://ngrl.manchester.ac.uk/LOVDv.2.0/ LOVD 2.0-28 5 genes 399 variants
NGRL, Manchester LOVD CHM,KDM6A,L1CAM,MLL2,UBE3A 327 unique
http://www-huge.uni-regensburg.de/BEST1_database/ LOVD 2.0-23 1 gene 394 variants
Bestrophin 1 (BEST1) BEST1 269 unique
http://www.dbagenes.unito.it/ LOVD 2.0-25 9 genes 364 variants
Diamond-Blackfan Anemia RPL11,RPL35A,RPL5,RPS10,RPS17,RPS19,R... 227 unique
https://grenada.lumc.nl/LOVD2/UCL-Heart/ LOVD 2.0-35 8 genes 361 variants
FH UCL BHF FTH1,HAMP,HFE2,LDLR,LDLRAP1,PCSK9,SLC... 332 unique
http://rpgr.hgu.mrc.ac.uk/ LOVD 1.1.0-05 1 gene 358 variants
Retinitis Pigmentosa GTPase Regulator database RPGR 358 unique
https://grenada.lumc.nl/LOVD2/ARC/ LOVD 2.0-35 2 genes 333 variants
LOVD - Leiden Open Variation Database VIPAR,VPS33B 251 unique
http://grenada.lumc.nl/LOVD2/ROR/ LOVD 2.0-35 2 genes 291 variants
LOVD 2.0 - ROR genes ROR1,ROR2 55 unique
http://grenada.lumc.nl/LOVD2/WS/ LOVD 2.0-35 5 genes 279 variants
LOVD - Leiden Open Variation Database EDN3,EDNRB,MITF,PAX3,SOX10 233 unique
http://grenada.lumc.nl/LOVD2/ctx/ LOVD 2.0-35 1 gene 211 variants
Cerebrotendinous Xanthomatosis CYP27A1 69 unique
http://www.icp.ucl.ac.be/vikkula/VAdb/ LOVD 2.0-35 16 genes 207 variants
Vascular Anomaly and Lymphedema Mutation Database CCBE1,CCM2,FLT4,FOXC2,GATA2,GJC2,GLMN... 137 unique
https://grenada.lumc.nl/LOVD2/PAX2/ LOVD 2.0-35 1 gene 196 variants
PAX2 variant database PAX2 61 unique
https://drdb.gene.le.ac.uk/ LOVD 2.0-35 4 genes 184 variants
Death Receptor Database (DRdb) TNFRSF10A,TNFRSF10B,TNFRSF10C,TNFRSF10D 144 unique
http://149.142.212.78/LOVD/ LOVD 2.0-31 1 gene 174 variants
UCLA Neurogenetics SETX Database SETX 107 unique
http://grenada.lumc.nl/LOVD2/amc/ LOVD 2.0-35 1 gene 163 variants
LOVD - Leiden Open Variation Database PORCN 116 unique
http://www.skingenedatabase.com/ LOVD 2.0-16 1 gene 150 variants
The Folliculin Mutation Database FLCN 84 unique
http://nndimontreal.ca/ LOVD 3.0-03 2 genes 133 variants
LOVD - Leiden Open Variation Database AQP2,AVPR2 8 unique
https://grenada.lumc.nl/LOVD2/uni-hd/5-HT/ LOVD 2.0-35 5 genes 117 variants
University of Heidelberg Serotonin variant database HTR3A,HTR3B,HTR3C,HTR3D,HTR3E 58 unique
http://www.goldenhelix.org/server/a1atvar/ LOVD 2.0-30 1 gene 93 variants
a1atvar SERPINA1 65 unique
http://ROGDI.i-med.ac.at LOVD 2.0-34 1 gene 54 variants
ROGDI MUI ROGDI 9 unique
http://www.icp.ucl.ac.be/vikkula/CLPdb/ LOVD 2.0-35 1 gene 50 variants
Cleft Lip and Palate Mutation Database IRF6 40 unique
https://grenada.lumc.nl/LOVD2/BCM/ LOVD 2.0-35 1 gene 29 variants
Baylor College of Medicine KAT6B 23 unique
https://grenada.lumc.nl/LOVD2/TCS/ LOVD 2.0-35 2 genes 26 variants
Treacher Collins syndrome variant database POLR1C,POLR1D 22 unique
http://FKBP14.i-med.ac.at LOVD 2.0-34 1 gene 12 variants
FKBP14 MUI FKBP14 2 unique
https://grenada.lumc.nl/LOVD2/NIH/eyegene/ LOVD 2.0-35 1 gene 2 variants
LOVD - Leiden Open Variation Database PRPF8 2 unique
http://www.medgen.mcgill.ca/nndi/ LOVD 2.0-16 1 gene 2 variants
nndi AVP 1 unique
http://www.med.uni-magdeburg.de/lovd/ LOVD 2.0-26 1 gene 2 variants
Magdeburg Mutation Database LAMB2 1 unique
http://www.medgen.mcgill.ca/ANO5/ LOVD 2.0-24 1 gene 1 variants
ANO5 LOVD - Leiden Open Variation Database ANO5 1 unique
https://grenada.lumc.nl/LOVD2/CILD/ LOVD 2.0-35 5 genes 0 variants
Primary Ciliary Dyskinesia variant database DNAAF1,DNAH11,DNAH5,DNAI1,DNAI2 0 unique
https://grenada.lumc.nl/LOVD2/vumc/CTD/ LOVD 2.0-35 4 genes 0 variants
Connective tissue disorders (VUMC Amsterdam) ACTA2,COL10A1,COL4A1,MYH11 0 unique
http://genetics.genomicscenter.nl/LOVD_UMC/ LOVD 3.0-03 2 genes 0 variants
UMCU LOVD NOC2L,SAMD11 0 unique
http://HSD17B10.i-med.ac.at LOVD 2.0-34 1 gene 0 variants
HSD17B10 MUI HSD17B10 0 unique
https://atlas.cmm.ki.se/LOVDv.2.0/ LOVD 2.0-31 1 gene 0 variants
LOVD - Leiden Open Variation Database MLH1 0 unique
http://grenada.lumc.nl/LOVD2/L1CAM/ LOVD 2.0-35 1 gene 0 variants
LOVD - Leiden Open Variation Database L1CAM 0 unique
http://CNDP1.i-med.ac.at LOVD 2.0-34 0 genes 0 variants
CNDP1 MUI 0 unique
http://dnadb.info/ LOVD 2.0-31 0 genes 0 variants
International DNA Database 0 unique
http://AUH.i-med.ac.at LOVD 2.0-34 0 genes 0 variants
AUH MUI 0 unique
http://ACAD8.i-med.ac.at LOVD 2.0-34 0 genes 0 variants
ACAD8 - MUI 0 unique
https://grenada.lumc.nl/LOVD2/CDG/ LOVD 2.0-35 0 genes 0 variants
Congenital disorders of glycosylation (CDG) 0 unique
http://ACADSB.i-med.ac.at LOVD 2.0-34 0 genes 0 variants
ACADSB MUI 0 unique
http://HMGCS2.i-med.ac.at LOVD 2.0-34 0 genes 0 variants
HMGCS2 MUI 0 unique
http://brca.iarc.fr/LOVD/ LOVD 2.0-22 ? genes ? variants
LOVD - IARC ? unique
(This list is updated daily and shows LOVD 2.0 installations active for the last three months that have the "include in the global LOVD listing" setting enabled. Please allow one day for changes to take effect. Also, known 1.1.0 installations have been added.)

Last modified 2013/01/23 16:42:05 CET

When using or discussing LOVD please refer to:
Fokkema IF, Taschner PE, Schaafsma GC, Celli J, Laros JF, den Dunnen JT (2011). LOVD v.2.0: the next generation in gene variant databases. Hum Mutat. 2011 May;32(5):557-63.

LOVD has received funding from the European Community's Seventh Framework Programme
(FP7/2007-2013) under grant agreement nº 200754 - the GEN2PHEN project.
Leiden University Medical Center, Netherlands
Ing. Ivo F.A.C. Fokkema, Dr. Johan T. den Dunnen