LOVD v.3.0 - Leiden Open Variation Database
Online gene-centered collection and display of DNA variants
Query all public LOVD installations
Query all public LOVD instances:
Examples: Precise: chr15:g.40699840C>T,
Instead of "chr15", you can also use a reference sequence, e.g., NC_000015.9:g.40699840C>T.
The given build will then be derived from your input.
LOVDs currently support only one genome build; if no results are found, you may want to repeat your query using a different genome build.
LOVD contains for hg18 ~2K unique variants, hg19 ~3.0M unique variants, and hg38 ~1.4M.
This service queries the variant's location, i.e. results of other variants on the same location will show as well. When searching using a ranged variant in HGVS format, only variants exactly matching that range will be returned. When searching using a range (2nd example above), all variants within that range will be returned (to a max of 50).
When using or discussing LOVD please refer to:
Fokkema IF, Kroon M, López Hernández JA, Asscheman D, Lugtenburg I, Hoogenboom J, den Dunnen JT.
The LOVD3 platform: efficient genome-wide sharing of genetic variants.
Eur J Hum Genet (2021).